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GenomeCast, GenomeQuest GeneRef Max, mpiBlast 1.3.0, Ensembl, UCSC Human Genome Browser, Isentris, Quantian, FieldScreen


Gene-IT has launched two new products: GenomeCast and GenomeQuest GeneRef Max. GenomeCast is a “genomic broadcast network” that automatically downloads content from worldwide sequence repositories and more than 9.6 million patented sequences. The information is cross-referenced and indexed before being broadcast directly to customer servers. GenomeQuest GeneRef Max cross-references microarray probe sets with more than 266,000 gene transcripts from six public data sources and millions of patent sequence records, and is available for distribution over GenomeCast, Gene-IT said.

mpiBlast 1.3.0 is available from Los Alamos National Laboratory at The release includes several enhancements, including use of the latest NCBI Toolbox; E-value scores that are identical to scores reported by NCBI Blast; and database and results pipelining to speed up the database distribution and reduce memory requirements for large query sets.

Ensembl has released a preliminary assembly for the Monodelphis domestica (opossum) genome at The assembly has a coverage of around 7.19X, and spans 3.6 billion bases (including gaps).

The University of California Santa Cruz Genome Bioinformatics Group has released the SNP annotation track for the Build 35 (hg17) UCSC Human Genome Browser ( The SNP data were obtained from dbSNP Build 123. Users now have the ability to filter the SNP data based on validation status, functional class, variant class, average heterozygosity, and other features.

Elsevier MDL has begun shipping its Isentris suite of products, the successor to MDL’s ISIS platform. Isentris consists of four products: the MDL Base user interface, the MDL Draw chemical drawing software, the MDL Core Interface middle tier, and MDL Direct chemical data cartridges for molecules and reactions.

Quantian, an extension of the Knoppix Linux distribution tailored for numerical and quantitative analysis, is available at It includes a complete installation of BioConductor, BioPerl, EMBOSS, and other scientific applications and visualization tools.

Cresset BioMolecular Discovery has launched FieldScreen, a software package that selects leads for targets based on electrostatic, steric, and hydrophobic molecular fields rather than molecular structure. According to the company, the software can find novel hits by screening just a few hundred compounds rather than hundreds of thousands.


Filed under

The Scan

And For Adolescents

The US Food and Drug Administration has authorized the Pfizer-BioNTech SARS-CoV-2 vaccine for children between the ages of 12 and 15 years old.

Also of Concern to WHO

The Wall Street Journal reports that the World Health Organization has classified the SARS-CoV-2 variant B.1.617 as a "variant of concern."

Test for Them All

The New York Times reports on the development of combined tests for SARS-CoV-2 and other viruses like influenza.

PNAS Papers on Oral Microbiome Evolution, Snake Toxins, Transcription Factor Binding

In PNAS this week: evolution of oral microbiomes among hominids, comparative genomic analysis of snake toxins, and more.