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GeneX-Lite, EON 1.0, WABE 1.3, EMBOSS, MEV, GeneChip Operating Software

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The National Center for Genome Resources has launched a new version of the GeneX-Lite gene expression database client with an improved user interface and enhanced annotation capabilities at http://www.ncgr.org/genex.


OpenEye Scientific Software has released EON 1.0, an electrostatics comparison program that screens databases of molecules for similarity to a lead compound. The company has also released WABE 1.3, a lead optimization program that generates isoteric analogs to a lead molecule with the same shape but more desirable electrostatics.


Researchers at the Belgian and Argentinian EMBnet nodes have posted a beta release of EMBOSS wrappers for Clustal, Blast, Fasta, and other programs at http://www.wemboss.org/Folder.2003-09-11.4050/Folder.2003-09-11.2502/wrappers4EMBOSS-0.1b.tar.gz.


The TM4 software group at the Institute for Genomic Research has released MEV (multiple experiment viewer) 3.0 at http://www.tigr.org/software/tm4/mev.html. New features include a scripting option for running multiple algorithms successively, and improved cluster table viewers. Four new analysis modules have also been added: Expression Analysis Systematic Explorer; two-factor ANOVA; K-nearest neighbors classifier; and Gene Distance Matrix.


Affymetrix has released version 1.2 of its GeneChip Operating Software (GCOS). GCOS 1.2 offers new data sharing tools; 50-60 percent faster creation of CEL files; compatibility with higher-density arrays; and 21 CFR 11 compliance.

 

Filed under

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.