The National Center for Genome Resources has launched a new version of the GeneX-Lite gene expression database client with an improved user interface and enhanced annotation capabilities at http://www.ncgr.org/genex.
OpenEye Scientific Software has released EON 1.0, an electrostatics comparison program that screens databases of molecules for similarity to a lead compound. The company has also released WABE 1.3, a lead optimization program that generates isoteric analogs to a lead molecule with the same shape but more desirable electrostatics.
Researchers at the Belgian and Argentinian EMBnet nodes have posted a beta release of EMBOSS wrappers for Clustal, Blast, Fasta, and other programs at http://www.wemboss.org/Folder.2003-09-11.4050/Folder.2003-09-11.2502/wrappers4EMBOSS-0.1b.tar.gz.
The TM4 software group at the Institute for Genomic Research has released MEV (multiple experiment viewer) 3.0 at http://www.tigr.org/software/tm4/mev.html. New features include a scripting option for running multiple algorithms successively, and improved cluster table viewers. Four new analysis modules have also been added: Expression Analysis Systematic Explorer; two-factor ANOVA; K-nearest neighbors classifier; and Gene Distance Matrix.
Affymetrix has released version 1.2 of its GeneChip Operating Software (GCOS). GCOS 1.2 offers new data sharing tools; 50-60 percent faster creation of CEL files; compatibility with higher-density arrays; and 21 CFR 11 compliance.