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Genetic Association Database, Lasergene 7.1, UniProt 9.0

An updated version of the Genetic Association Database, an archive of published gene-based human disease genetic association studies, is available here. The content has increased from 8,000 records to more than 28,000 records. The new version also includes a batch search function, which allows users to paste in a list of human gene symbols, Unigene numbers, or Entrez Gene numbers to query the database.

DNAStar has released Lasergene 7.1, which includes SeqMan Pro, a new assembly engine that is compatible with next-generation sequencing technologies. Lasergene 7.1 runs natively on Windows, Mac PowerPC chips, and Mac Intel chips and also enables batch import of Vector NTI files while retaining key formatting features from those files. 

UniProt 9.0 is available here. The release includes 3,554,507 entries, including 241,242 in the UniProtKB/Swiss-Prot section and 3,313,265 in the UniProtKB/TrEMBL section.

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The Scan

Wolf Howl Responses Offer Look at Vocal Behavior-Related Selection in Dogs

In dozens of domestic dogs listening to wolf vocalizations, researchers in Communication Biology see responses varying with age, sex, reproductive status, and a breed's evolutionary distance from wolves.

Facial Imaging-Based Genetic Diagnoses Appears to Get Boost With Three-Dimensional Approach

With data for more than 1,900 individuals affected by a range of genetic conditions, researchers compared facial phenotype-based diagnoses informed by 2D or 3D images in the European Journal of Human Genetics.

Survey Suggests Multigene Cancer Panel VUS Reporting May Vary Across Genetic Counselors

Investigators surveyed dozens of genetic counselors working in clinical or laboratory settings, uncovering attitudes around VUS reporting after multigene cancer panel testing in the Journal of Genetic Counseling.

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.