Version 4.0 of Redwood City, Calif.-based Silicon Genetics’ GeneSpring gene expression analysis software will be available March 31.
Improvements over version 3.2 include the ability to load different file formats and determine which normalizations are appropriate, as well as the ability to compute error models.
Pyrosequencing of Uppsala, Sweden, has released SNP Software AQ for allele frequency determination.
SNP Software AQ can be used with SNP reagent kits and Pyrosequencing’s PSQtm96 system to automatically quantify allele frequencies in pooled DNA samples.
MDL Information Systems, based in San Leandro, Calif., has released a free database containing information on selected compounds found to be active in the National Cancer Institute’s AIDS antiviral screen.
The database is accessible to researchers who use MDL’s ISIS (Integrated Scientific Information System) software and allows them to view chemical structures, compound names, registry numbers, and quantitative screening results.
New York-based ProteoMetrics has released the SonarMS/MS search engine to identify proteins using MS/MS information from digest peptides. It can search DNA from the genome as well as translated protein sequences, allowing for detection of exons, alternate splice sites, and novel genes.
SonarMS/MS takes a protein/ EST/chromosome segment and looks at a compilation of mass spectra to see whether there is good evidence for that sequence.