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GeneSifter.Net, Centera Compliance Edition, Zebrafish whole genome shotgun assembly dataset, AnnHyb, European Bioinformatics Institute, NPACI Rocks, DAG-Edit

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VizX Labs has released a new update to GeneSifter.Net. Enhancements include the LOWESS normalization techniques, Holm and Bonferroni p-value correction methods, Welch’s t-test, and Kruskal-Wallis non-parametric tests. The update also offers dynamic Gene Ontology navigation, which allows researchers to add information on molecular function.

 

EMC has launched Centera Compliance Edition, a content-addressed storage system designed to meet records retention regulations for fixed content or unchanging data. New features include retention enforcement, which enables compliance officers to set hardened retention periods on electronic records; and application access security, which ensures the privacy of sensitive records for regulations.

 

Ensembl has released a preliminary zebrafish whole genome shotgun assembly dataset at http://pre.ensembl.org/Danio_rerio/. The assembly contains 1,452,210,772 base pairs in 83,470 supercontigs.

 

A beta version of AnnHyb, software for working with and managing nucleotide sequences in multiple formats, is available at http://annhyb.free.fr. Features include sequence annotation, restriction analysis, pattern searching, and retrieval from servers. AnnHyb is released under GPL and run under Windows.

 

Promotorwise, a new program that compares two sequences, considering translocations and inversions, is available from the European Bioinformatics Institute at www.ebi.ac.uk/Wise2/promoterwise.html.

 

The National Partnership for Advanced Computational Infrastructure (NPACI) at the San Diego Supercomputer Center and the University of California, Berkeley, has released version 2.3.2 of the NPACI Rocks Linux cluster toolkit. The release is the first co-release for both Itanium2- and x86-based clusters, and is freely available at www.rocksclusters.org.

 

Version 1.318 of the Gene Ontology Consortium’s DAG-Edit ontology curation tool has now become available for downoad at http://sourceforge.net/projects/geneontology.

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The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.