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GeneSifter Core Edition, XP Glide, UniProt 2.0, ADME/tox databases, Smack 1.0, UCSC Genome Browser, Ensembl, EMBOSS 2.9.0


VizX Labs has released GeneSifter Core Edition — a new version of the company’s microarray analysis system designed for core facilities. Core Edition adds administrative tools that allow core facilities to provide and manage GeneSifter accounts for their clients, the company said. Computing and storage resources are provided via off-site secure servers and the facility staff can assign these resources to multiple user accounts.

Schrödinger has released a new version of its XP (extra-precision) Glide docking software that includes a new sampling algorithm and scoring function to improve docking accuracy by eliminating false positives. Further information is available at:

UniProt 2.0 is now available from the European Bioinformatics Institute, the Swiss Institute of Bioinformatics, and the Protein Information Resource at The release contains 1,487,788 entries (153,871 from UniProt/SwissProt, and 1,333,917 from UniProt/Trembl).

Bio-Rad’s informatics division has released thirteen new ADME/tox databases. The databases include data related to the blood brain barrier, human intestinal absorption, log D, log P, mutagenicity, plasma-protein binding, and water solubility.

OpenEye Scientific Software has released Smack 1.0, which converts substructure and reaction queries expressed in MDL file formats to Daylight’s Smarts strings.

Concurrent with the release of the draft assembly of the dog (Canis familiaris) genome last week, the University of California Santa Cruz genome bioinformatics group has released a Genome Browser and Blat server, as well as dog sequence and annotation data at Ensembl has also released a preliminary assembly of the dog genome at The sequence for the dog genome is based on 7.6X coverage and contains around 2.5 billion base pairs.

EMBOSS 2.9.0 is available at New features include modifications to ACD and the libraries as part of the development of an EMBOSS ontology. In addition, Embassy packages can now be compiled and linked against an installed version of EMBOSS.

Filed under

The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more