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GeneGo Donates Pathway Maps to ISICR

NEW YORK (GenomeWeb News) – The International Society for Interferon and Cytokine Research will offer its members access to manually curated pathway maps donated by GeneGo, the company said today.

The bioinformatics company said the 41 canonical pathway maps it has donated to ISICR describe the role of interferons and cytokines in immune response, development, call cycle, apoptosis, survival, cell adhesion, and chemotaxis.

ISICR is a non-profit organization that includes more than 650 scientists involved in molecular biology, interferon, cytokine and chemokine cell biology, and biochemical research.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.