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GeneData, The Gladstone Institute of Cardiovascular Disease, Ensembl

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GeneData of Basel, Switzerland, has released version 2.0 of GeneData Impressionist, its enterprise-wide proteomics research software. The new version offers novel methods for the quality assessment of 2D gel and mass spectrometry data, according to the company, as well as improved scripting capabilities for automating analysis.

The Gladstone Institute of Cardiovascular Disease at the University of California, San Francisco, has released MAPPFinder, an application for microarray data analysis using the annotations of the GO. MAPPFinder carries out an automated analysis of the entire GO, identifying those GO terms that are showing correlated gene expression changes in a microarray experiment. A beta release of MAPPFinder is available for download free of charge from www.GenMAPP.org.

Version 6.5 of the Pathway Tools software and BioCyc, a collection of pathway/genome databases, is now available at BioCyc.org. Upgrades to BioCyc include Pathway/Genome Navigator software for Sun and PC platforms, expanded flatfile versions of the BioCyc databases, and new databases for Vibrio cholerae strain N16961 and Mycobacterium tuberculosis strain CDC1551. The database for Mycobacterium tuberculosis strain H37Rv has also been re-created. Enhancements to Pathway Tools software include an expanded viewer for adding expression data to the full metabolic overview. A license agreement must be signed to download the software or databases. Contact [email protected] for information.

Ensembl annotation for NCBI human build 30 is now available at http://www.ensembl.org/Homo_sapiens. According to the Ensembl developers, NCBI 30 is of much higher quality than previous builds because it is the first to be const- ructed directly from the internal maps held in the chromosome finishing centers that are providing the sequence for finishing the human genome. The new release contains 22,980 gene predictions with 27,628 transcripts.

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The Scan

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