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GeneData, Genomic Solutions.


GeneData of Basel, Switzerland, plans to release a new version of its Phylosopher genome analysis product by the end of the month. Phylosopher 3.5 will enable gene expression analysis and expand the product’s genome coverage from mostly bacterial and fungal organisms to include C. elegans, Drosophila and human data.

Kerstin Braig, GeneData’s product manager for Phylosopher, said that the new version would provide integrated access to the capabilities of the company’s Expressionist package, which is used to analyze gene expression arrays. The two products would continue to exist independently, she said, and customers would be able to purchase the separate packages or the linked version. Phylosopher has attracted “a few new customers,” Braig said, but declined to identify them pending GeneData’s official announcement later this month.

Phylosopher uses GeneData’s proprietary algorithms and protein family database to compare and analyze complete genomes. It includes phylogenetic profiling, in silico prediction of protein interactions, and automated operon analysis. The package features a graphical “Genome Browser” as well as project management capabilities.

Genomic Solutions has added mouse, rat, and rat p450 microarrays to its GeneMap pre-printed microarray product line. These products are available now under a special early access agreement and will become generally available in January 2001. The company said it could also produce custom microarrays. Genomic Solutions developed the arrays under an agreement that provides it access to Research Genetics’ library of cDNA.

The mouse and rat arrays each contain 1,700 genes, and the oligonucleotide-based p450 rat arrays contain 300 genes. Genomic Solutions plans to market the p450 array as an inexpensive alternative to early drug discovery assays currently performed using protein enzymes. The company also plans to offer additional arrays for most of the 5,000 mouse and 17,500 rat genes in Research Genetics’ libraries.

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