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Gene Logic, Tripos, Memorial Sloan-Kettering, Integrative Cancer Biology Program, Nonlinear Dynamics


Gene Logic's Revenues Slip, Net Losses Widen

Gene Logic posted $17 million in total revenues for the third quarter ending on Sept. 30, down from revenues of $17.7 million for the year-ago quarter, the company said last week. Revenues for the company’s information business were $11.9 million, down slightly from $12.3 million in the third quarter of 2003.

The company said that its net losses for the quarter increased to $14.6 million from $10 million for the year-ago quarter. Gene Logic attributed this loss to a $9 million charge for purchased research and development associated with the acquisition of the Horizon technology from Millennium on July 23.

Gene Logic spent $631,000 on research and development in the quarter, up from $540,000 for the year-ago period.

The company reported cash and cash equivalents of $47 million on hand, and marketable securities of $60.1 million, down from $49 million and $63 million, respectively, on hand at Dec. 31, 2003.

Tripos Q3 Revenues Increase 16 Percent

Tripos reported $16.1 million in total receipts for quarter ended Sept. 30 last week, a 16 percent increase over $13.8 million in the third quarter of 2003.

Third-quarter R&D spending also increased, to $16.1 million from $13.8 million, the company said.

Tripos also posted a loss of $145,000, or $.02 per share, compared to net income of $964,000, or $.11 per share, for the same period one year ago.

Tripos had $4.8 million in cash and equivalents as of Sept. 30.

MSKCC Seeks Comp Bio Faculty

The Computational Biology Center at Memorial Sloan-Kettering Cancer Center in New York is recruiting research faculty.

According to an MSKCC recruitment notice, tenure-track positions are available for junior and senior faculty who will run independent research labs. MSKCC said it plans to grow to seven faculty members — up from its current level of two - with a total of 80 people by 2006.

Further information is available at and

NCI Earmarks $14.9M for Integrative Cancer Biology Program

The National Cancer Institute said last week that it has set aside $14.9 million in funding for a new Integrative Cancer Biology Program, which will support nine centers devoted to integrative and multi-disciplinary cancer research.

The centers will integrate technologies such as genomics, proteomics, and molecular imaging, to generate computer and mathematical models that could predict the cancer process, NCI said.

“The key aspect that sets the ICBP effort apart from others is the focus on building predictive cancer models, and not just analyzing data,” said Daniel Gallahan, associate director of NCI’s division of cancer biology, in a statement.

NCI’s Cancer Biomedical Information Grid (caBIG) program will coordinate all the bioinformatics software needed by the ICBP.

The ICBP centers and project titles are:

  • Massachusetts General Hospital, “Development of a Virtual Tumor;”
  • Dana-Farber Cancer Institute, “Signatures of Kinase Activation in Cancer;”
  • Lawrence Berkeley National Laboratory, “Systems-Based Predictions of Response to Cancer Therapy;”
  • Ohio State University, “Interrogating Epigenetic Changes in Cancer Genomes;”
  • Massachusetts Institute of Technology, “Regulatory Networks in Cancer Initiation and Progression;”
  • University Hospital of Cleveland, “Complex Systems and Control of MMR-Deficient Cells;”
  • Duke University, “Integration of Oncogenic Networks in Cancer Phenotypes;”
  • Stanford University School of Medicine, “Computational Modeling of Cancer Biology;”
  • Vanderbilt University Medical Center, “Multiscale Mathematical Modeling of Cancer Invasion.”

Nonlinear Dynamics Expands Distribution Agreement with Elchrom

Nonlinear Dynamics said last week that it has expanded a distribution agreement with Elchrom Scientific of Cham, Switzerland, for its TotalLab software package.

Elchrom Scientific has distributed TotalLab throughout Europe over the past five years. Under the new contract, Nonlinear said it has established an annual license agreement with Elchrom Scientific to distribute TotalLab worldwide.


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