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Funding Update: NSF Bioinformatics Grants Awarded Oct 23 — Nov 19, 2013


Modeling Protein Degradation — Evaluation of Strategies and Targets
Start Date: Nov. 15, 2013
Expires: Oct. 31, 2015
Awarded Amount to Date: $300,000
Principal Investigators: Christine Vogel, Dennis Shasha
Sponsor: New York University

According to the abstract, the funds will support the use of mass spectrometry and bioinformatics to combine proteomic data such as protein ubiquitination status and degradation, with information on protein sequence and structure to discover features that impact protein stability.

Development and Application of Multi-scale Modeling for Biomolecular Association
Start Date: May 1, 2014
Expires: April 30, 2019
Awarded Amount to Date: $351,038
Principal Investigators: Chia-en Chang
Sponsor: University of California, Riverside

According to the abstract, the investigators will combine "multi-level coarse-grained and atomistic simulations to efficiently and accurately model molecular associations and kinetic enhancement of the enzymes and nanoparticle systems." The methods developed as part of this project are expected to "improve understanding of protein-ligand binding kinetics and assist the design of nanostructures, nanoparticles, and engineered enzymes."

Filed under

The Scan

Shape of Them All

According to BBC News, researchers have developed a protein structure database that includes much of the human proteome.

For Flu and More

The Wall Street Journal reports that several vaccine developers are working on mRNA-based vaccines for influenza.

To Boost Women

China's Ministry of Science and Technology aims to boost the number of female researchers through a new policy, reports the South China Morning Post.

Science Papers Describe Approach to Predict Chemotherapeutic Response, Role of Transcriptional Noise

In Science this week: neural network to predict chemotherapeutic response in cancer patients, and more.