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Funding Update: NSF Bioinformatics Grants Awarded Oct. 19 — Dec. 21. 2011


Exact and Approximate Algorithms for 3D Structure Modeling of Protein-Protein Interactions
Start Date: July 1, 2012
Expires: June 30, 2017
Awarded Amount to Date: $95,431
Principal Investigator: Jinbo Xu
Sponsor: Toyota Technological Institute at Chicago

Supports research efforts focused on creating algorithms for 3D structure modeling of protein-protein interactions that will be used to enrich large-scale PPI networks as well as to verify experimental PPIs and predict novel ones. The abstract states that the investigator will use a number of techniques, including graph minor theory, probabilistic graphical models, dual relaxation, and decomposition, to "understand the mathematical structure of the problem" and design efficient algorithms.

Models and Algorithms for Comparative Analysis of Biological Networks
Start Date: Feb. 1, 2012
Expires: Jan. 31, 2017
Awarded Amount to Date: $69,640
Principal Investigator: Byung-Jun Yoon
Sponsor: Texas Engineering Experiment Station

This award supports the development of a mathematical framework and methods for comparative analysis of genome-scale biological networks that could be used to identify novel pathways as well as explore their functions and mechanisms. According to the abstract, the investigator will develop a multi-state semi-Markov random walk model for probabilistic comparison of large-scale networks as well as algorithms for querying and aligning them.

Building a Comprehensive Catalog of Conserved Alternative Splicing Events from Heterogeneous Data
Start Date: Aug. 1, 2011
Expires: July 31, 2014
Awarded Amount to Date: $574,124
Principal Investigator: Liliana Florea
Sponsor: Johns Hopkins University

Supports efforts to build catalogs of conserved alternative splicing events from heterogeneous sequence data. The investigator intends to produce novel software tools that can align various types of sequence data to a target genome as well as construct models of genes and their splice variants and map them between species.

Filed under

The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more