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Funding Update: NSF Bioinformatics Grants Awarded Nov 20 — Dec 30, 2013

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A Learning Drug Discovery Platform in the Cloud
Start Date: Jan. 1, 2014
Expires: June 30, 2014
Awarded Amount to Date: $150,000
Principal Investigator: Christian Lang
Sponsor: Acelot

According to the abstract, these funds will support the development of a web-based platform for drug discovery and optimization.


Statistical Modeling of Short-read Counts in RNA-seq
Start Date: July 15, 2013
Expires: July 31, 2014
Awarded Amount to Date: $118,151
Principal Investigator: Wenxuan Zhong
Sponsor: University of Georgia Research Foundation

According to the abstract, the investigators will use the funds to develop modeling software "for estimating gene expression levels from RNA-seq data and identifying marker genes reacting to specific pathogens in a unified framework."


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The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.