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Funding Update: NSF Bioinformatics Grants Awarded Nov 20 — Dec 30, 2013

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A Learning Drug Discovery Platform in the Cloud
Start Date: Jan. 1, 2014
Expires: June 30, 2014
Awarded Amount to Date: $150,000
Principal Investigator: Christian Lang
Sponsor: Acelot

According to the abstract, these funds will support the development of a web-based platform for drug discovery and optimization.


Statistical Modeling of Short-read Counts in RNA-seq
Start Date: July 15, 2013
Expires: July 31, 2014
Awarded Amount to Date: $118,151
Principal Investigator: Wenxuan Zhong
Sponsor: University of Georgia Research Foundation

According to the abstract, the investigators will use the funds to develop modeling software "for estimating gene expression levels from RNA-seq data and identifying marker genes reacting to specific pathogens in a unified framework."


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The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.