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Funding Update: NSF Bioinformatics Grants Awarded Mar. 21 — Apr. 19, 2013


Visualization and Statistics for Spatial Population Genomic Analysis
Start Date: May 1, 2013
Expires: April 30, 2016
Awarded Amount to Date: $327,156
Principal Investigator: Graham Coop
Sponsor: University of California, Davis

According to the abstract, the funds will support the development of methods and software that can generate maps from genomic data and also map samples of unknown origin. These tools could be used to identify the origins of new parasites, "identify key barriers dividing the range of an endangered species" and infer ancestry among other uses.

An integrated Systems Engineering Approach to the Modeling of Cellular Dynamics and Bioreactors
Start Date: April 1, 2013
Expires: March 31, 2016
Awarded Amount to Date: $143,986
Principal Investigators: Jin Wang, Thomas Jeffries, Qinghua He
Sponsor: Auburn University

According to the abstract, the funds will be used to develop a model that can adequately describe the dynamics of cellular metabolism. Specifically, the investigators intend to develop a computational framework called flux balance analysis guided dynamic programming, FBA-DP, that will be used to "model the dynamics of cellular metabolism" that will be coupled with an experimental procedures and equipment that "have been developed to obtain dynamic process information required by the computational component."

Developing a 3D Browser to Explore Genomes
Start Date: Feb. 1, 2013
Expires: Sept 30, 2016
Awarded Amount to Date: $342,813
Principal Investigator: Wenjin Zheng
Sponsor: University of Texas, Health Science Center Houston

According to the abstract, the investigators intend to further develop a proof-of-concept interactive 3D viewer, dubbed Genome3D, that will help researchers integrate and visualize their genomic and epigenomic data. Specifically, they intend to build a platform independent system that biologists can use to build and refine 3D genome models for analyzing their data

Filed under

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.