A Sequence-indexed Reverse Genetics Resource for Maize: A Set of Lines with Single Ds-GFP Insertions Spread throughout the Genome
Start Date: April 15, 2014
Expires: March 31, 2017
Awarded Amount to Date: $661,650
Principal Investigators: Hugo Dooner, Chunguang Du
Sponsor: Rutgers University
According to the abstract, these funds will be used to "complete the production of a reverse genetics resource based on the transposon Ds that will enable the community to generate and build up a single-gene knockout resource for maize."
Development of Bioinformatic Methods for Studying Gene Expression Network Inflammation and Neuronal Regeneration
Start Date: Dec. 1, 2013
Expires: July 31, 2015
Awarded Amount to Date: $283,650
Principal Investigator: Yi Ren
Sponsor: Florida State University
The abstract states that these funds will be used to develop bioinformatic and statistical methods for studying trauma to the "central nervous system including [the] spinal cord, which provokes an inflammatory response that generates substantial secondary tissue damage and inhibits neuronal regeneration."
Genetic Architecture and the Evolution of Recombination
Start Date: April 15, 2014
Expires: March 31, 2017
Awarded Amount to Date: $269,548
Principal Investigator: Ricardo Azevedo
Sponsor: University of Houston
These funds will support the development of "new empirical and modeling frameworks for studying the evolution of genetic exchange," according to the abstract. Specifically, the investigator will "extend an existing mathematical model of virus replication to capture the short-term evolutionary dynamics of experimental virus populations; determine whether gene interactions evolve in the virus model as predicted from simpler, less realistic, models; and experimentally test the predictions obtained from the mathematical model in real virus populations."