Skip to main content
Premium Trial:

Request an Annual Quote

Funding Update: NSF Bioinformatics Grants Awarded Apr. 20 — May 24, 2013


Continued Development of RaptorX Server for Protein Structure and Functional Prediction
Start Date: July 1, 2013
Expires: June 30, 2016
Awarded Amount to Date: $551,238
Principal Investigator: Jinbo Xu
Sponsor: Toyota Technological Institute at Chicago

According to the abstract, the funds will be used to “transform RaptorX, a popular protein structure modeling web server, to one that can also annotate functions of a protein sequence and the quality of a theoretical protein model in the absence of the corresponding native structure.” This will “facilitate the interpretation and proper usage of a theoretical protein model” as well as “predict functions of a protein sequence with coverage beyond what can be reached by native-structure-based methods and accuracy much higher than sequence-based methods,” the investigator wrote.

A Systematic Computational Approach to Creating Libraries of High-Quality Mass Spectra for Unidentified Metabolites
Start Date: Sept. 1, 2013
Expires: Aug. 31, 2016
Awarded Amount to Date: $580,611
Principal Investigator: Xiuxia Du
Sponsor: University of North Carolina, Charlotte

According to the abstract, the funds will be used to develop a computational workflow for creating “libraries of high-quality mass spectra for unknown metabolites that are observed repeatedly by mass spectrometers in metabolomics studies.”

Multivariate Statistical Methods for Genomic Data Integration
Start Date: June 1, 2013
Expires: May 31, 2016
Awarded Amount to Date: $177,027
Principal Investigator: Debashis Ghosh
Sponsor: Pennsylvania State University, University Park

The abstract states that the funds will support research into “multivariate methods of analysis with high-dimensional genomic data that relax the linearity assumption.” According to the investigator, “the methodology will be evaluated using several real datasets as well as through simulation studies.”

Filed under

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.