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Funding Update: NIH Bioinformatics Grants Awarded Nov. 4 — Dec. 7, 2011


Project Title: Folding, Mis-Folding, and Aggregation of Small Proteins
Principal Investigator: Hansmann, Ulrich H.E.
Organization: University of Oklahoma, Norman
Project Start Date: June 1, 2003
Project End Date: June 30, 2013
Funding Institute: NIGMS
FY Total Cost: $183,290

Project Title: Extending Bayesian Phylogenetic Analysis
Principal Investigator: Huelsenbeck, John P.
Organization: University of California, Berkeley
Project Start Date: Aug. 1, 2004
Project End Date: Nov. 30, 2013
Funding Institute: NIGMS
FY Total Cost: $261,268

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The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.