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Funding Update: NIH Bioinformatics Grants Awarded Nov. 4 — Dec. 7, 2011

Dec 10, 2011
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Project Title: Folding, Mis-Folding, and Aggregation of Small Proteins
Principal Investigator: Hansmann, Ulrich H.E.
Organization: University of Oklahoma, Norman
Project Start Date: June 1, 2003
Project End Date: June 30, 2013
Funding Institute: NIGMS
FY Total Cost: $183,290

Project Title: Extending Bayesian Phylogenetic Analysis
Principal Investigator: Huelsenbeck, John P.
Organization: University of California, Berkeley
Project Start Date: Aug. 1, 2004
Project End Date: Nov. 30, 2013
Funding Institute: NIGMS
FY Total Cost: $261,268

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Informatics
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The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.