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Funding Update: NIH Bioinformatics Grants Awarded March 13, — April 24, 2014

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Part 1 of 2

Project Title: Genomic Database for the Yeast Saccharomyces
Principal Investigator: Cherry, Joe
Organization: Stanford University
Project Start Date: Sept. 30, 1995
Project End Date: Feb. 29, 2016
Funding Institute: NHGRI
FY Total Cost: $2,699,376


Project Title: AMD Genetics: Methods and Analysis for Progression, Prediction, and Association
Principal Investigator: Chen, Wei
Organization: University of Pittsburgh
Project Start Date: April 1, 2014
Project End Date: March 31, 2017
Funding Institute: NEI
FY Total Cost: $301,073


Project Title: Informatics Platform for Mammalian Gene Regulation at Isoform-level
Principal Investigator: Davuluri, Ramana
Organization: Northwestern University, Chicago
Project Start Date: May 2, 2013
Project End Date: April 30, 2016
Funding Institute: NLM
FY Total Cost: $152,050


Project Title: Development of Trans Proteomic Pipeline, An Analysis Suite for Mass Spectrometry
Principal Investigator: Deutsch, Eric
Organization: Institute for Systems Biology
Project Start Date: April 1, 2009
Project End Date: March 31, 2018
Funding Institute: NIGMS
FY Total Cost: $521,297


Project Title: Developing Reliable Insilico Methods to Design Small Molecules Targeting RNA
Principal Investigator: Disney, Matthew
Organization: Scripps Florida
Project Start Date: April 5, 2012
Project End Date: March 31, 2016
Funding Institute: NIGMS
FY Total Cost: $376,200


Project Title: Computational Structure-based Protein Design
Principal Investigator: Donald, Bruce
Organization: Duke University
Project Start Date: April 15, 2008
Project End Date: Feb. 28, 2018
Funding Institute: NIGMS
FY Total Cost: $319,289


Project Title: Bayesian Statistics and Algorithms for Homology Modeling
Principal Investigator: Dunbrack, Roland
Organization: Research Institute of Fox Chase Cancer Center
Project Start Date: May 15, 2008
Project End Date: March 31, 2017
Funding Institute: NIGMS
FY Total Cost: $339,150


Project Title: Methods for Evolutionary Informed Network Analysis to Discover Disease Variation
Principal Investigator: Dudley, Joel
Organization: Ichan School of Medicine at Mount Sinai
Project Start Date: April 1, 2013
Project End Date: March 31, 2017
Funding Institute: NIDDK
FY Total Cost: $414,442


Project Title: Statistical Methods for Ultrahigh-dimensional Biomedical Data
Principal Investigator: Fan, Jianqing
Organization: Princeton University
Project Start Date: Dec. 1, 2004
Project End Date: Jan 31, 2018
Funding Institute: NIGMS
FY Total Cost: $308,918


Project Title: Model Comparison in Structural Biology
Principal Investigator: Fraser, James
Organization: University of California, San Francisco
Project Start Date: April1, 2014
Project End Date: March 31, 2016
Funding Institute: NIGMS
FY Total Cost: $190,878


Project Title: Genomes In Eye Disease: Methods to Query Variants Across Multiple Genome-wide Datasets
Principal Investigator: Gaasterland, Theresa
Organization: University of California, San Francisco
Project Start Date: April1, 2012
Project End Date: March 31, 2015
Funding Institute: NEI
FY Total Cost: $339,325


Project Title: FlyBase: A Drosophila Genomic and Genetic Database
Principal Investigator: Gelbart, William
Organization: Harvard University
Project Start Date: Aug. 1, 1992
Project End Date: Dec. 31, 2014
Funding Institute: NHGRI
FY Total Cost: $1,275,764


Project Title: Online Mendelian Inheritance In Man (OMIM)
Principal Investigator: Hamosh, Ada
Organization: Johns Hopkins University
Project Start Date: June 12, 2012
Project End Date: Feb. 28, 2015
Funding Institute: NHGRI
FY Total Cost: $2,090,374


Project Title: Sequence-based Analysis of Parasite Diversity and Host Interactions
Principal Investigator: Kirkness, Ewen
Organization: J. Craig Venter Institute
Project Start Date: April 4, 2014
Project End Date: March 31, 2019
Funding Institute: NIAID
FY Total Cost: $208,968


Project Title: Computational Tools for the Analysis of High-throughput Immunoglobulin Sequencing
Principal Investigator: Kleinstein, Steven
Organization: Yale University
Project Start Date: April 15, 2014
Project End Date: March 31, 2018
Funding Institute: NIAID
FY Total Cost: $400,816


Project Title: Web Software for Drug Targeting Signaling Networks in Primary Cell Subsets
Principal Investigator: Kotecha, Nikesh
Organization: Cytobank
Project Start Date: Feb. 9, 2011
Project End Date: March 31, 2016
Funding Institute: NIGMS
FY Total Cost: $750,000


Project Title: Novel Statistical Approaches to Mental Health Phenotype Analysis in GWA Studies
Principal Investigator: Lange, Christoph
Organization: Harvard University School of Public Health
Project Start Date: Dec. 7, 2007
Project End Date: March 31, 2015
Funding Institute: NIMH
FY Total Cost: $374,348


Project Title: Statistical Methods for Gene Mapping
Principal Investigator: Lange, Kenneth
Organization: University of California, Los Angeles
Project Start Date: Aug. 1, 1995
Project End Date: March 31, 2016
Funding Institute: NIGMS
FY Total Cost: $544,393


Project Title: GenomeSpace: Community Web Environment for Analysis Across Diverse Genomic Tools
Principal Investigator: Mesirov, Jill
Organization: Broad Institute
Project Start Date: March 17, 2014
Project End Date: Feb. 28, 2018
Funding Institute: NHGRI
FY Total Cost: $1,890,000


Project Title: Bioconductor: An Open Computing Resource for Genomics
Principal Investigator: Morgan, Martin
Organization: Fred Hutchinson Cancer Research Center
Project Start Date: Sept. 28, 2006
Project End Date: Feb. 28, 2016
Funding Institute: NHGRI
FY Total Cost: $1,169,604


Project Title: Democratization of Data Analysis in Life Sciences Through Galaxy
Principal Investigator: Nekrutenko, Anton
Organization: Pennsylvania State University
Project Start Date: Feb. 22, 2012
Project End Date: Dec. 31, 2015
Funding Institute: NHGRI
FY Total Cost: $1,409,638


Project Title: The Meme Suite of Motif-based Sequence Analysis Tools
Principal Investigator: Noble, William
Organization: University of Washington
Project Start Date: Sept. 28, 2009
Project End Date: March 31, 2018
Funding Institute: NIGMS
FY Total Cost: $399,671


Project Title: Linking Sequence and Copy Number Variation to Eye Diseases by Regulatory Genomics
Principal Investigator: Park, Peter
Organization: Brigham and Women's Hospital
Project Start Date: April 1, 2014
Project End Date: March 31, 2017
Funding Institute: NEI
FY Total Cost: $397,688


Project Title: Refinement Methods for Protein Docking Based on Exploring Multi-dimensional Energ[y]
Principal Investigator: Paschalidis, Ioannis
Organization: Boston University
Project Start Date: April 1, 2010
Project End Date: March 31, 2015
Funding Institute: NIGMS
FY Total Cost: $316,023

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