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Funding Update: NIH Bioinformatics Grants Awarded June 28 — August 3, 2012, Part 2

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Part 2 of 2. Part 1, which ran last week, is available here.

Project Title: Mathematically Modeling the Regulation of Immune Responses to HIV Infection
Principal Investigator: Hoffmann, Alexander
Organization: Salk Institute for Biological Studies
Project Start Date: Not Listed
Project End Date: Not Listed
Funding Institute: NIAID
FY Total Cost: $339,882


Project Title: Continued Development and Support of Essential SBML Infrastructure
Principal Investigator: Hucka, Michael
Organization: California Institute of Technology
Project Start Date: Feb. 1, 2004
Project End Date: June 30, 2013
Funding Institute: NIGMS
FY Total Cost: $572,497


Project Title: Technology Development for a MolBio Knowledgebase
Principal Investigator: Hunter, Lawrence
Organization: University of Colorado, Denver
Project Start Date: Dec. 1, 2003
Project End Date: July 31, 2013
Funding Institute: NLM
FY Total Cost: $596,909


Project Title: Study Protein Folding Mechanism Using a Roadmap-based Approach
Principal Investigator: Huo, Shuanghong
Organization: Clark University
Project Start Date: Aug. 1, 2009
Project End Date: July 31, 2014
Funding Institute: NIGMS
FY Total Cost: $247,299


Project Title: Statistical Methods for Analysis and Integration in Genomic Studies of Disease
Principal Investigator: Kendziorski, Christina
Organization: University of Wisconsin, Madison
Project Start Date: Aug. 1, 2012
Project End Date: April 30, 2016
Funding Institute: NIGMS
FY Total Cost: $274,360


Project Title: Computational Biology Scientific Research Support Component
Principal Investigator: Kepler, Thomas
Organization: Duke University
Project Start Date: Not Listed
Project End Date: Not Listed
Funding Institute: NIAID
FY Total Cost: $1,329,030


Project Title: Identification of Regulatory Cancer Risk SNPs for Chemoprevention Discovery
Principal Investigator: Klein, Robert
Organization: Sloan-Kettering Institute for Cancer Research
Project Start Date: Aug. 2, 2012
Project End Date: July 31, 2014
Funding Institute: NCI
FY Total Cost: $91,450


Project Title: SOLAR-Eclipse Computational Tools for Imaging Genetics
Principal Investigator: Kochunov, Peter
Organization: University of Maryland, Baltimore
Project Start Date: Aug. 1, 2012
Project End Date: July 31, 2015
Funding Institute: NIBIB
FY Total Cost: $378,222


Project Title: Enhancing Genome-Wide Association Studies Via Integrative Network Analysis
Principal Investigator: Koyuturk, Mehmet
Organization: Case Western Reserve University
Project Start Date: Aug. 1, 2012
Project End Date: July 31, 2016
Funding Institute: NLM
FY Total Cost: $315,810


Project Title: Integrated Analysis of High Throughput Cancer Genomic Data
Principal Investigator: Li, Yi
Organization: University of Michigan, Ann Arbor
Project Start Date: Aug. 11, 2011
Project End Date: July 31, 2013
Funding Institute: NCI
FY Total Cost: $116,267


Project Title: Novel Computational Methods for Modeling Cytochrome P450 Mediated Drug Metabolism
Principal Investigator: Lill, Markus Alexander
Organization: Purdue University, West Lafayette
Project Start Date: Sept. 1, 2010
Project End Date: July 31, 2015
Funding Institute: NIGMS
FY Total Cost: $202,003


Project Title: Continued Development and Maintenance of the 3DNA Suite of Programs
Principal Investigator: Lu, Xiang-Jun
Organization: Columbia University
Project Start Date: Sept. 19, 2011
Project End Date: June 30, 2016
Funding Institute: NIGMS
FY Total Cost: $234,852


Project Title: Arabidopsis N-Regulatory Network Dynamics: Integrating Metabolome and Transcriptome
Principal Investigator: Marshall Colon, Amy
Organization: New York University
Project Start Date: Aug. 1, 2010
Project End Date: July 31, 2013
Funding Institute: NIGMS
FY Total Cost: $53,972


Project Title: Integrative Statistical Methods and Tools for Analysis of Perturbation Signatures
Principal Investigator: Medvedovic, Mario
Organization: University of Cincinnati
Project Start Date: Sept. 24, 2011
Project End Date: June 30, 2013
Funding Institute: NHLBI
FY Total Cost: $381,625


Project Title: Novel Tree-Based Statistical Methods for Cancer Risk Prediction
Principal Investigator: Molinaro, Annette
Organization: University of California, San Francisco
Project Start Date: July 10, 2012
Project End Date: April 30, 2016
Funding Institute: NCI
FY Total Cost: $335,601


Project Title: Structural Genomics of Eukaryotic Domain Families
Principal Investigator: Montelione, Gaetano
Organization: Rutgers The State University of New Jersey, New Brunswick
Project Start Date: Sept 1, 2010
Project End Date: June 30, 2015
Funding Institute: NIGMS
FY Total Cost: $7,576,532


Project Title: Bioinformatics Approaches to Visual Disease Genetics
Principal Investigator: Moore, Jason
Organization: Dartmouth College
Project Start Date: Aug. 1, 2012
Project End Date: June 30, 2015
Funding Institute: NEI
FY Total Cost: $322,000


Project Title: Bioconductor: An Open Computing Resource for Genomics
Principal Investigator: Morgan, Martin
Organization: Fred Hutchinson Cancer Research Center
Project Start Date: Sept. 28, 2006
Project End Date: Feb. 29, 2016
Funding Institute: NHGRI
FY Total Cost: $1,235,329


Project Title: IDASH: Integrating Data for Analysis, Anonymization, and Sharing
Principal Investigator: Ohno-Machado, Lucila
Organization: University of California, San Diego
Project Start Date: Sept. 20, 2010
Project End Date: June 30, 2015
Funding Institutes: NIH, NHLBI, NHGRI, NIBIB, and NLM
FY Total Cost: $3,350,164


Project Title: A New Model of Peptide Fragmentation for Improved Protein Identification
Principal Investigator: Old, William Marland
Organization: University of Colorado, Boulder
Project Start Date: Sept. 1, 2011
Project End Date: July 31, 2016
Funding Institute: NCI
FY Total Cost: $314 ,363


Project Title: Neuroinformatics for Gene Expression: Network, Function, and Meta-Analysis
Principal Investigator: Pavlidis, Paul
Organization: University of British Columbia
Project Start Date: Aug. 1, 2005
Project End Date: June 30, 2015
Funding Institute: NIGMS
FY Total Cost: $240 ,537


Project Title: Bioinformatics Approach to Influenza A/H1N1 Vaccine Immune Profiling
Principal Investigator: Poland, Gregory
Organization: Mayo Clinic
Project Start Date: July 1, 2011
Project End Date: June 30, 2015
Funding Institute: NIAID
FY Total Cost: $6,982,503


Project Title: Software for the Analysis of Large-Scale Genotyping and Sequencing Studies
Principal Investigator: Purcell, Shaun
Organization: Mount Sinai School of Medicine
Project Start Date: Sept. 27, 2010
Project End Date: June 30, 2013
Funding Institute: NHGRI
FY Total Cost: $335,610

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Project Title: Automated Spectral Data Transformations and Analysis Pipeline for High Throughput
Principal Investigator: Rajwa, Bartlomiej
Organization: Purdue University, West Lafayette
Project Start Date: July 1, 2012
Project End Date: June 30, 2014
Funding Institute: NIBIB
FY Total Cost: $198,990


Project Title: Integrating Model Validation and Improvement with Structure
Principal Investigator: Richardson, Jane Shelby
Organization: University of California, Lawrence Berkeley National Laboratory
Project Start Date: Not Listed
Project End Date: Not Listed
Funding Institute: NIGMS
FY Total Cost: $182,361


Project Title: XCMS-Online: An Integrated Platform for Metabolic Profile Analysis and Metabolite
Principal Investigator: Rinehart, Duane
Organization: Metaboscientia
Project Start Date: July 6, 2012
Project End Date: Dec. 31, 2013
Funding Institute: NIGMS
FY Total Cost: $176,970


Project Title: Computational and Statistical Models for Human Genetics
Principal Investigator: Rocha Abecasis, Goncalo
Organization: University of Michigan, Ann Arbor
Project Start Date: July 18, 2012
Project End Date: April 30, 2017
Funding Institute: NHGRI
FY Total Cost: $619,118


Project Title: Whole Transcriptome Analysis for Neurobiology
Principal Investigator: Ryutov, Alex
Organization: Epicenter Software
Project Start Date: July 1, 2008
Project End Date: May 31, 2014
Funding Institute: NINDS
FY Total Cost: $436,189


Project Title: Application of Boolean Networks to Discover Stem and Progenitor Cells
Principal Investigator: Sahoo, Debashis
Organization: Stanford University
Project Start Date: July 1, 2011
Project End Date: June 30, 2013
Funding Institute: NCI
FY Total Cost: $152,135


Project Title: Risk Prediction and Computational Tools for Cancer Patient Adherence
Principal Investigator: Sairamesh, Jakka
Organization: 360Fresh
Project Start Date: Sept. 28, 2009
Project End Date: July 31, 2014
Funding Institute: NCATS
FY Total Cost: $542,509


Project Title: Modeling RNA Tertiary Structure Folding by a Hierarchical Framework
Principal Investigator: Schlick, Tamar
Organization: New York University
Project Start Date: Sept. 9, 2011
Project End Date: June 30, 2015
Funding Institute: NIGMS
FY Total Cost: $389,366


Project Title: Identifying Population-Level Variation in Cross-Sectional and Longitudinal [Human Microbiome Project] Studies
Principal Investigator: Schloss, Patrick David
Organization: University of Michigan, Ann Arbor
Project Start Date: Sept. 27, 2010
Project End Date: June 30, 2013
Funding Institute: NHGRI
FY Total Cost: $375,842


Project Title: LINCS Information Framework (LIFE) to Integrate and Analyze Diverse Dataset[s]
Principal Investigator: Schurer, Stephan
Organization: University of Miami School of Medicine
Project Start Date: Sept. 24, 2011
Project End Date: June 30, 2013
Funding Institute: NHLBI
FY Total Cost: $373,856


Project Title: Computational and Mathematical Modeling for Biomedical Systems
Principal Investigator: Secomb, Timothy
Organization: University of Arizona
Project Start Date: July 1, 2009
Project End Date: June 30, 2014
Funding Institute: NIGMS
FY Total Cost: $200,183


Project Title: Functional Assessment of Genes and Common Genetic Risk Variants in Ovarian Cancer
Principal Investigator: Sellers, Thomas
Organization: Moffitt Cancer Center
Project Start Date: Not Listed
Project End Date: Not Listed
Funding Institute: NCI
FY Total Cost: $767,203


Project Title: Kinetic Studies of Protein Folding
Principal Investigator: Sosnick, Tobin
Organization: University of Chicago
Project Start Date: Aug. 1, 1996
Project End Date: July 31, 2013
Funding Institute: NIGMS
FY Total Cost: $346,214


Project Title: Bayesian Joint Estimation of Alignment and Phylogeny
Principal Investigator: Suchard, Marc
Organization: University of California, Los Angeles
Project Start Date: Aug. 1, 2008
Project End Date: July 31, 2013
Funding Institute: NIGMS
FY Total Cost: $295,220


Project Title: New Methods and Enhanced Software for Predicting Functional SNPs
Principal Investigator: Sunyaev, Shamil
Organization: Brigham and Women’s Hospital
Project Start Date: April 1, 2006
Project End Date: April 30, 2016
Funding Institute: NIGMS
FY Total Cost: $365,925


Project Title: Semi-Parametric Methods for Gene-Environment Interaction
Principal Investigator: Tchetgen Tchetgen, Eric Joel
Organization: Harvard University School of Public Health
Project Start Date: July 20, 2012
Project End Date: April 30, 2016
Funding Institute: NIEHS
FY Total Cost: $343,246


Project Title: PRO: A Protein Ontology in OBO Foundry for Integration of Biomedical Knowledge
Principal Investigator: Wu, Cathy
Organization: University of Delaware
Project Start Date: May 1, 2007
Project End Date: June 30, 2015
Funding Institute: NIGMS
FY Total Cost: $785,773


Project Title: Prediction and Network Construction Using High-Throughput Data
Principal Investigator: Yeung-Rhee, Ka Yee
Organization: University of Washington
Project Start Date: Sept. 1, 2008
Project End Date: June 30, 2013
Funding Institute: NIGMS
FY Total Cost: $136,976


Project Title: Continued Improvement of Genome Assemblies and Assembly Techniques for Next Generation [Sequencing]
Principal Investigator: Yorke, James
Organization: University of Maryland, College Park
Project Start Date: Aug. 13, 2003
Project End Date: May 31, 2014
Funding Institute: NHGRI
FY Total Cost: $288,125


Project Title: itNETZ: Integrative and Translational Network-based Cellular Signature Analyzer
Principal Investigator: Zhou, Xiaobo
Organization: Methodist Hospital Research Institute
Project Start Date: Sept 24, 2011
Project End Date: June 30, 2013
Funding Institute: NHLBI
FY Total Cost: $388,750


Project Title: RNA 3D Motif Search, Atlas, and Prediction from Sequence
Principal Investigator: Zirbel, Craig
Organization: Bowling Green State University
Project Start Date: Aug. 10, 2010
Project End Date: July 31, 2014
Funding Institute: NIGMS
FY Total Cost: $304,899


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