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Funding Update: NIH Bioinformatics Grants Awarded July 10 — Aug. 19, 2013

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Part 1 of 2

Project Title: Improved Algorithms for Structure Refinement at Multiple Resolution
Principal Investigator: Adams, Paul
Organization: University of California, Lawrence Berkeley Laboratory
Project Start Date: Not Listed
Project End Date: Not Listed
Funding Institute: NIGMS
FY Total Cost: $961,997


Project Title: Phenix: New Methods for Automation in Macromolecular Crystallography
Principal Investigator: Adams, Paul
Organization: University of California, Lawrence Berkeley Lab
Project Start Date: Jul1 1, 2001
Project End Date: July 31, 2014
Funding Institute: NIGMS
FY Total Cost: $1, 705,779


Project Title: DelPhi: Software for Electrostatic Modeling of Biomolecules and Objects
Principal Investigator: Alexov, Emil
Organization: Clemson University
Project Start Date: Aug. 10, 2010
Project End Date: July 31, 2015
Funding Institute: NIGMS
FY Total Cost: $389,873


Project Title: Genetic Analysis of Common Diseases: An Evaluation
Principal Investigator: Almasy, Laura
Organization: Texas Biomedical Research Institute
Project Start Date: April 10, 1983
Project End Date: July 31, 2017
Funding Institute: NIGMS
FY Total Cost: $627,619


Project Title: GEISHA: A Chicken Embryo Gene Expression Resource
Principal Investigator: Antin, Parker
Organization: University of Arizona
Project Start Date: Sept. 30, 2010
Project End Date: July 31, 2015
Funding Institute: NICHD
FY Total Cost: $698,873


Project Title: High Resolution Structure Modeling with Rosetta
Principal Investigator: Baker, David
Organization: University of Washington
Project Start Date: April 1, 2010
Project End Date: Mar. 31, 2014
Funding Institute: NIGMS
FY Total Cost: $262,869


Project Title: An Integrated System to Monitor Complex Tissues at Single-cell Resolution
Principal Investigator: Bao, Zhirong
Organization: Memorial Sloan-Kettering Cancer Center
Project Start Date: Sept. 24, 2012
Project End Date: July 31, 2017
Funding Institute: NICHD
FY Total Cost: $663,751


Project Title: Removing Statistical Bottlenecks in Data Analysis for the ENCODE Consortium
Principal Investigator: Bickel, Peter
Organization: University of California, Berkeley
Project Start Date: Sept. 17, 2012
Project End Date: June 30, 2015
Funding Institute: NHGRI
FY Total Cost: $403,326


Project Title: BigData: Low Memory Streaming Pre-filters for Biological Sequencing Data
Principal Investigator: Brown, Charles
Organization: Michigan State University
Project Start Date: July 19, 2013
Project End Date: May 31, 2016
Funding Institute: NHGRI
FY Total Cost: $249,888


Project Title: High Resolution Analysis of Transcription Factors' DNA Binding Specificities
Principal Investigator: Bulyk, Martha
Organization: Brigham and Women's Hospital
Project Start Date: July 26, 2006
Project End Date: May 31, 2016
Funding Institute: NHGRI
FY Total Cost: $628,890


Project Title: Inferring Gene Regulatory Circuitry from Functional Genomics Data
Principal Investigator: Bussemaker, Harmen
Organization: Columbia University
Project Start Date: Dec. 1, 2003
Project End Date: June 30, 2016
Funding Institute: NHGRI
FY Total Cost: $529,956


Project Title: Computational Design of Specific Binding Proteins Using Leave-one-out
Principal Investigator: Bystroff, Christopher
Organization: Rensselaer Polytechnic Institute
Project Start Date: Sept. 20, 2012
Project End Date: July 31, 2017
Funding Institute: NIGMS
FY Total Cost: $306,898


Project Title: Robust Approaches to the Development and Evaluation of Prognostic Classifiers
Principal Investigator: Cai, Tianxi
Organization: Harvard University, School of Public Health
Project Start Date: June 1, 2007
Project End Date: June 30, 2015
Funding Institute: NIGMS
FY Total Cost: $155,848


Project Title: Multiscale Analysis of Genomic and Cellular Networks (MAGNET)
Principal Investigator: Califano, Andrea
Organization: Columbia University
Project Start Date: Sept. 26, 2005
Project End Date: July 31, 2015
Funding Institute: NCI
FY Total Cost: $3,272,760


Project Title: Family-based Rare Variant Association Methods for Quantitative Traits
Principal Investigator: Chen, Wei Min
Organization: University of Virginia
Project Start Date: Aug. 1, 2012
Project End Date: July 31, 2014
Funding Institute: NHGRI
FY Total Cost: $79,000


Project Title: An Integrated Approach to Dissect the Functional Network of Large Non-coding Data
Principal Investigator: Chen, Yiwen
Organization: Dana Farber Cancer Institute
Project Start Date: Aug. 1, 2013
Project End Date: July 31, 2015
Funding Institute: NCI
FY Total Cost: $112,476


Project Title: Multiscale Framework for Molecular Heterogeneity Analysis
Principal Investigator: Cooper, Lee
Organization: Emory University
Project Start Date: Aug. 1, 2013
Project End Date: July 31, 2016
Funding Institute: NLM
FY Total Cost: $162,319


Project Title: Harnessing GTEx to Create Transcriptome Knowledge and Inform Disease Biology
Principal Investigator: Cox, Nancy
Organization: University of Chicago
Project Start Date: Aug. 1, 2013
Project End Date: June 30, 2016
Funding Institute: NIMH
FY Total Cost: $626,060


Project Title: Systematic Data Curation and Integration to Link Models of Human Disease
Principal Investigator: Dolinski, Kara
Organization: Princeton University
Project Start Date: Sept. 14, 2011
Project End Date: July 31, 2015
Funding Institute: NIH
FY Total Cost: $607,237


Project Title: Association Analysis Software for Mining Clinical Next-gen Sequencing Data
Principal Investigator: Durfee, Timothy
Organization: DNAStar
Project Start Date: Sept. 25, 2012
Project End Date: June 30, 2015
Funding Institute: NHGRI
FY Total Cost: $485,252


Project Title: Biocomputation Across Distributed Private Datasets to Enhance Drug Discovery
Principal Investigator: Ekins, Sean
Organization: Collaborative Drug Discovery
Project Start Date: Aug. 16, 2013
Project End Date: July 31, 2016
Funding Institute: NCATS
FY Total Cost: $462,944


Project Title: Statistical Genetics Methods for Mixed Pathologies
Principal Investigator: Fardo, David
Organization: University of Kentucky
Project Start Date: Aug. 15, 2013
Project End Date: May 31, 2016
Funding Institute: NIA
FY Total Cost: $148,361


Project Title: Mouse Phenotyping Informatics Infrastructure
Principal Investigator: Flicek, Paul
Organization: European Molecular Biology Laboratory
Project Start Date: Sept. 16, 2011
Project End Date: July 31, 2016
Funding Institute: NHGRI
FY Total Cost: $1,940,000


Project Title: Computational Methods for Structural-functional Studies of Proteins
Principal Investigator: Grishin, Nick
Organization: University of Texas, Southwestern Medical Center
Project Start Date: July 1, 2010
Project End Date: June 30, 2014
Funding Institute: NIGMS
FY Total Cost: $296,207


Project Title: Semantic Lamhdi: Linking Diseases to Model Organism Resources
Principal Investigator: Haendel, Melissa
Organization: Oregon Health and Science University
Project Start Date: Sept. 1, 2012
Project End Date: July 31, 2016
Funding Institute: NIH
FY Total Cost: $1,239,600


Project Title: EMERGE Coordinating Center
Principal Investigator: Hanes, Jonathan
Organization: Vanderbilt University Medical Center
Project Start Date: Aug. 15, 2011
Project End Date: July 31, 2015
Funding Institute: NHGRI
FY Total Cost: $958,512


Project Title: Mathematically Modeling the Regulation of Immune Responses to HIV-infection
Principal Investigator: Hoffmann, Alexander
Organization: Salk Institute for Biological Studies
Project Start Date: Not Listed
Project End Date: Not Listed
Funding Institute: NIAID
FY Total Cost: $323,641


Project Title: Enhancing the GMOD Suite of Genome Annotation and Visualization Tools
Principal Investigator: Holmes, Ian
Organization: University of California, Berkeley
Project Start Date: Sept. 1, 2007
Project End Date: May 31, 2014
Funding Institute: NHGRI
FY Total Cost: $376,156


Project Title: Study Protein Folding Mechanism Using a Roadmap-based Approach
Principal Investigator: Huo, Shuanghong
Organization: Clark University
Project Start Date: Aug. 1, 2009
Project End Date: July 31, 2014
Funding Institute: NIGMS
FY Total Cost: $238,644

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