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Funding Update: NIH Bioinformatics Grants Awarded Dec. 7, 2011 — Feb. 9, 2012

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Project Title: Computationally Optimized Anti-Staphylococcal Biotherapeutics
Principal Investigator: Bailey-Kellogg, Chris
Organization: Dartmouth College
Project Start Date: Feb. 1, 2012
Project End Date: Jan. 31, 2014
Funding Institute: NIAID
FY Total Cost: $210,421


Project Title: A Turnkey System for High-Throughput Variant Discovery and Interpretation
Principal Investigator: Ding Li
Organization: Washington University
Project Start Date: Feb. 1, 2012
Project End Date: Dec. 31, 2015
Funding Institute: NHGRI
FY Total Cost: $805,000


Project Title: Robust Software Tools for Variant Identification and Functional Assessment
Principal Investigator: Marth, Gabor
Organization: Boston College
Project Start Date: Feb. 1, 2012
Project End Date: Dec. 31, 2015
Funding Institute: NHGRI
FY Total Cost: $1,010,000


Project Title: Accurate Analysis of Genome Structural Variation Using Large-Scale Sequence Data
Principal Investigator: McCarroll, Steven Andrew
Organization: Harvard University
Project Start Date: Feb. 1, 2012
Project End Date: Dec. 31, 2015
Funding Institute: NHGRI
FY Total Cost: $448,000


Project Title: Scripps Genome Adviser: Annotation and Distributed Variant Interpretation Server
Principal Investigator: Torkamani, Ali
Organization: Scripps Health
Project Start Date: Feb. 1, 2012
Project End Date: Dec. 31, 2015
Funding Institute: NHGRI
FY Total Cost: $382,000


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The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.