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Funding Update: NIH Bioinformatics Grants Awarded April 5 — May 24, 2012

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Part 1 of 2

Project Title: Leukemia Stem Cell Antigen Discovery Using Advanced Genomic and Proteomic Methods
Principal Investigator: Armistead, Paul Michael
Organization: University of North Carolina, Chapel Hill
Project Start Date: May 1, 2012
Project End Date: Feb. 28, 2015
Funding Institute: NHLBI
FY Total Cost: $132,088


Project Title: Widely Distributed Software for Using Mass Spectrometry to Identify Glycans
Principal Investigator: Bern, Marshall Wayne
Organization: Palo Alto Research Center
Project Start Date: July 19, 2010
Project End Date: April 30, 2014
Funding Institute: NIGMS
FY Total Cost: $409,927


Project Title: Development of Technologies for Genome-Wide Identification of RNA Branch Points
Principal Investigator: Burge, Christopher B.
Organization: Massachusetts Institute of Technology
Project Start Date: April 24, 2012
Project End Date: Feb. 28, 2015
Funding Institute: NHGRI
FY Total Cost: $268,105


Project Title: Inferring Gene Regulatory Circuitry from Functional Genomics Data
Principal Investigator: Bussemaker, Harmen J.
Organization: Columbia University
Project Start Date: Aug. 13, 2004
Project End Date: April 30, 2013
Funding Institute: NHGRI
FY Total Cost: $381,046


Project Title: Mapping the Drugome: Predictive Network Approaches to Drug Safety Surveillance
Principal Investigator: Cami, Aurel B.
Organization: Children's Hospital Boston
Project Start Date: April 1, 2011
Project End Date: March 31, 2013
Funding Institute: NLM
FY Total Cost: $130,845


Project Title: Structural Bioinformatics Software for Epitope Selection and Antibody Engineering
Principal Investigator: Darnell, Steven Joseph
Organization: DNAStar
Project Start Date: May 15, 2012
Project End Date: Dec. 15, 2012
Funding Institute: NIGMS
FY Total Cost: $156,708


Project Title: Identification of Novel Therapeutics for Tuberculosis Combining Cheminformatics, Diverse Databases, and Logic-based Pathway Analysis
Principal Investigator: Ekins, Sean
Organization: Collaborative Drug Discovery
Project Start Date: July 1, 2010
Project End Date: April 30, 2014
Funding Institute: NIAID
FY Total Cost: $479,605


Project Title: Extension of the Sequence Ontology: Preparing for the (Re) Sequencing Revolution
Principal Investigator: Eilbeck, Karen Louise
Organization: University of Utah
Project Start Date: Aug. 15, 2007
Project End Date: April 30, 2014
Funding Institute: NHGRI
FY Total Cost: $294,487


Project Title: Membrane Protein Structure Modeling with Experimental Restraints
Principal Investigator: Fiser, Andras
Organization: Albert Einstein College of Medicine
Project Start Date: May 1, 2011
Project End Date: April 30, 2015
Funding Institute: NIGMS
FY Total Cost: $316,983


Project Title: Development of the Flexible Comparative Modeling Toolkit
Principal Investigator: Godzik, Adam
Organization: Sanford-Burnham Medical Research Institute
Project Start Date: May 1, 2012
Project End Date: April 30, 2016
Funding Institute: NIGMS
FY Total Cost: $370,500


Project Title: Integrative Analysis of a GWAS Repository with EMRs from over 40,000 Children
Principal Investigator: Hakonarson, Hakon
Organization: Children's Hospital of Philadelphia
Project Start Date: May 15, 2012
Project End Date: April 30, 2015
Funding Institutes: NHGRI, NICHD
FY Total Cost: $826,267


Project Title: Better Outcomes for Children: GWAS & PHEWAS in EMERGE II
Principal Investigator: Harley, John Barker
Organization: Children's Hospital Medical Center Cincinnati
Project Start Date: May 15, 2012
Project End Date: April 30, 2015
Funding Institutes: NHGRI, NICHD
FY Total Cost: $806,101


Project Title: Conversion of Short-Read Sequence Data to Locally-Assembled Long Contigs
Principal Investigator: Johnson, Eric A.
Organization: University of Oregon
Project Start Date: May 1, 2011
Project End Date: April 30, 2013
Funding Institute: NHGRI
FY Total Cost: $213,000


Project Title: RepBase Update – A Database of Repetitive Sequences
Principal Investigator: Jurka, Jerzy Wladyslaw
Organization: Genetic Information Research Institute
Project Start Date: Sept. 30, 1996
Project End Date: April 30, 2014
Funding Institute: NLM
FY Total Cost: $551,544


Project Title: Statistical Power Calculations for Chip-Seq Experiments
Principal Investigator: Keles, Sunduz
Organization: University of Wisconsin, Madison
Project Start Date: May 1, 2012
Project End Date: March 31, 2014
Funding Institute: NHGRI
FY Total Cost: $184,085


Project Title: Structural and Functional Consequences of Disease SNPs on the Transcriptome
Principal Investigator: Laederach, Alain T.
Organization: University of North Carolina, Chapel Hill
Project Start Date: May 1, 2012
Project End Date: April 30, 2016
Funding Institute: NIGMS
FY Total Cost: $273,639


Project Title: Novel Statistical Approaches to Mental Health Phenotype Analysis in GWA Studies
Principal Investigator: Lange, Christoph
Organization: Harvard University
Project Start Date: Dec. 1, 2007
Project End Date: March 31, 2015
Funding Institute: NIMH
FY Total Cost: $406,556


Project Title: Novel Web-Based Tools for Collaborative Community Driven Genome Feature Annotations
Principal Investigator: Lewis, Suzanna E.
Organization: University of California, Lawrence Berkeley Lab
Project Start Date: Aug. 1, 2007
Project End Date: April 30, 2014
Funding Institute: NIGMS
FY Total Cost: $623,221


Project Title: Imputation and Analysis of Rare Variants in Admixed Populations
Principal Investigator: Li, Yun
Organization: University of North Carolina, Chapel Hill
Project Start Date: May 16, 2012
Project End Date: Feb. 28, 2015
Funding Institute: NHGRI
FY Total Cost: $320,000


Project Title: Statistical Methods for Correlated and High-Dimensional Biomedical Data
Principal Investigator: Lin, Xihong
Organization: Harvard University
Project Start Date: Dec 15, 1997
Project End Date: March 31, 2016
Funding Institute: NCI
FY Total Cost: $308,344


Project Title: Bayesian Methods in Signal Transduction Network Analysis
Principal Investigator: Liu, Yin
Organization: University of Texas
Project Start Date: March 15, 2011
Project End Date: March 14, 2015
Funding Institute: NLM
FY Total Cost: $230,340


Project Title: Biological Annotation of TCGA Data
Principal Investigator: Mills, Gordon B.
Organization: University of Texas
Project Start Date: May 1, 2012
Project End Date: April 30, 2017
Funding Institute: NCI
FY Total Cost: $948,524


Project Title: Collaborative Development of Biomedical Ontologies and Terminologies
Principal Investigator: Musen, Mark A.
Organization: Stanford University
Project Start Date: March 1, 2009
Project End Date: Feb. 28, 2013
Funding Institute: NIGMS
FY Total Cost: $392,767


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