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Funding Update: NIH Bioinformatics Grants Awarded April 25 — June 2, 2014

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Project Title: Integrating Genomic and Environmental Perspectives on Internalizing Disorders
Principal Investigator: Adkins, Daniel
Organization: Virginia Commonwealth University
Project Start Date: April 1, 2011
Project End Date: Feb. 29, 2016
Funding Institute: NIMH
FY Total Cost: $131,576


Project Title: Software Tools for Regulatory Analysis of Large Cancer Methylome Datasets
Principal Investigator: Berman, Benjamin
Organization: University of Southern California
Project Start Date: May 13, 2014
Project End Date: Apr. 30, 2017
Funding Institute: NCI
FY Total Cost: $356,515


Project Title: Mapping Expression Quantitative Trait Loci with Next Generation Sequencing in SLE
Principal Investigator: Chen, Min
Organization: University of Texas, Dallas
Project Start Date: Feb. 1, 2013
Project End Date: Jan. 31, 2017
Funding Institute: NIAMS
FY Total Cost: $120,150


Project Title: Robust and Portable Workflow-based [Tools] for mRNA and Genome Resequencing
Principal Investigator: Chen, Ting
Organization: University of Southern California
Project Start Date: Feb. 1, 2012
Project End Date: Dec. 31, 2014
Funding Institute: NHGRI
FY Total Cost: $348,339


Project Title: Population Genetic Consequences of Recent Explosive Population Growth in Humans
Principal Investigator: Clark, Andrew
Organization: Cornell University
Project Start Date: May 10, 2014
Project End Date: Apr. 30, 2018
Funding Institute: NIGMS
FY Total Cost: $588,893


Project Title: Analysis of De Novo Mutation from Sequencing of Related Individuals and Cells
Principal Investigator: Conrad, Donald
Organization: Washington University
Project Start Date: May 8, 2014
Project End Date: Feb. 30, 2019
Funding Institute: NHGRI
FY Total Cost: $500,000


Project Title: Cancer Deep Phenotype Extraction from Electronic Medical Records
Principal Investigator: Crowley, Rebecca
Organization: University of Pittsburgh
Project Start Date: May 6, 2014
Project End Date: Apr. 30, 2019
Funding Institute: NCI
FY Total Cost: $696,805


Project Title: Informatics Platform for Mammalian Gene Regulation at Isoform-level
Principal Investigator: Davuluri, Ramana
Organization: Northwestern University at Chicago
Project Start Date: May 2, 2013
Project End Date: Apr. 30, 2016
Funding Institute: NLM
FY Total Cost: $337,196


Project Title: Simtk.org: A Resource to Enable Collaboration & Reproducibility of Biosimulations
Principal Investigator: Delp, Scott
Organization: Stanford University
Project Start Date: Sept. 1, 2013
Project End Date: Apr. 30, 2017
Funding Institute: NIGMS
FY Total Cost: $464,300


Project Title: Computational Tools to Analyze SNP Data from Patients with Mental Illness
Principal Investigator: Downey, Thomas
Organization: Partek
Project Start Date: June 17, 2009
Project End Date: March 31, 2016
Funding Institute: NIMH
FY Total Cost: $120,877


Project Title: Membrane Protein Structure Modeling with Experimental Restraints
Principal Investigator: Fiser, Andras
Organization: Albert Einstein College of Medicine
Project Start Date: May 1, 2011
Project End Date: April 30, 2015
Funding Institute: NIGMS
FY Total Cost: $317,300


Project Title: FlyBase: A Drosophila Genomic and Genetic Database
Principal Investigator: Gelbart, William
Organization: Harvard University
Project Start Date: Aug. 1, 1992
Project End Date: Dec. 31, 2014
Funding Institute: NHGRI
FY Total Cost: $106,443


Project Title: The Statistical and Computational Analysis of Flow Cytometry Data
Principal Investigator: Gottardo, Raphael
Organization: Fred Hutchinson Cancer Research Center
Project Start Date: May 1, 2008
Project End Date: Apr. 30, 2016
Funding Institute: NIBIB
FY Total Cost: $357,102


Project Title: NDEx — The Network Data Exchange, A Network Commons for Biologists
Principal Investigator: Ideker, Trey
Organization: University of California, San Diego
Project Start Date: May 1, 2014
Project End Date: Apr. 30, 2017
Funding Institute: NCI
FY Total Cost: $641,654


Project Title: Comparative Analysis of Genetic Interaction Networks
Principal Investigator: Ideker, Trey
Organization: University of California, San Diego
Project Start Date: Aug. 1, 2008
Project End Date: Feb. 28, 2018
Funding Institute: NIGMS
FY Total Cost: $480,934


Project Title: Computational Tools for Mining Large Amounts of ChIP and Gene Expression Data
Principal Investigator: Ji, Hongkai
Organization: Johns Hopkins University
Project Start Date: July 25, 2012
Project End Date: April 30, 2017
Funding Institute: NHGRI
FY Total Cost: $395,854


Project Title: Rosetta: An Integrated Macromolecular Modeling Suite
Principal Investigator: Kuhlman, Brian
Organization: University of North Carolina, Chapel Hill
Project Start Date: March 1, 2005
Project End Date: April 30, 2017
Funding Institute: NIGMS
FY Total Cost: $530,135


Project Title: Apollo: Collaborative, Interactive Analytics and Annotation of Genome Variants
Principal Investigator: Lewis, Suzanna
Organization: University of California
Project Start Date: Aug. 1, 2007
Project End Date: April 30, 2018
Funding Institute: NIGMS
FY Total Cost: $575,634


Project Title: Statistical Methods for Correlated and High-dimensional Biomedical Data
Principal Investigator: Lin, Xihong
Organization: Harvard University
Project Start Date: Dec. 15, 1997
Project End Date: March 31, 2016
Funding Institute: NCI
FY Total Cost: $299,093


Project Title: New Simulation Methods at Multi-scale and Resolutions
Principal Investigator: Ma, Jiangpeng
Organization: Baylor College of Medicine
Project Start Date: July 1, 2003
Project End Date: April 30, 2016
Funding Institute: NIGMS
FY Total Cost: $295,420


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Small Study of Gene Editing to Treat Sickle Cell Disease

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Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

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