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Funding Update: NIH Bioinformatics Grants Awarded Apr. 5 — May 2, 2013

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Project Title: Computational Tools to Analyze SNP Data from Patients with Mental Illness
Principal Investigator: Downey, Thomas
Organization: Partek
Project Start Date: June 17, 2009
Project End Date: Mar. 31, 2016
Funding Institute: NIMH
FY Total Cost: $598,866


Project Title: Genomes in Eye Disease: Methods to Query Variants Across Multiple Genome-wide Datasets
Principal Investigator: Gaasterland, Theresa
Organization: University of California, San Diego
Project Start Date: Apr. 1, 2012
Project End Date: Mar. 31, 2015
Funding Institute: NEI
FY Total Cost: $310,966


Project Title: Statistical Methods for Rare Variant Effects in Sequencing Association Studies
Principal Investigator: Lee, Seunggeun
Organization: Harvard University, School of Public Health
Project Start Date: June 15, 2012
Project End Date: Mar. 31, 2014
Funding Institute: NHLBI
FY Total Cost: $85,932


Project Title: Statistical Methods for Medical Tests and Biomarkers
Principal Investigator: Pepe, Margaret
Organization: Fred Hutchinson Cancer Research Center
Project Start Date: May 1, 1996
Project End Date: Mar. 31, 2016
Funding Institute: NIGMS
FY Total Cost: $300,435


Project Title: Bioinformatics and Information Technologies
Principal Investigator: Richman, Douglas
Organization: University of California, San Diego
Project Start Date: Not Listed
Project End Date: Not Listed
Funding Institute: NIAID
FY Total Cost: $18,861


Project Title: Methods for Pathway Modeling with Application to Folate
Principal Investigator: Thomas, Duncan
Organization: University of Southern California
Project Start Date: Aug. 16, 2010
Project End Date: Mar. 31, 2015
Funding Institute: NIEHS
FY Total Cost: $506,437


Project Title: Combined Computational and Experimental Analyses of Gene Regulation by MicroRNAs
Principal Investigator: Wang, Xiaowei
Organization: Washington University
Project Start Date: Apr. 1, 2010
Project End Date: Mar. 31, 2015
Funding Institute: NIGMS
FY Total Cost: $270,864


Project Title: Genome-Transcriptome-Phenome-wide Association: A New Paradigm for Association Studies
Principal Investigator: Xing, Poe
Organization: Carnegie-Mellon University
Project Start Date: May 15, 2009
Project End Date: Mar. 31, 2015
Funding Institute: NIGMS
FY Total Cost: $444,935


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The Scan

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.

Analysis of Endogenous Parvoviral Elements Found Within Animal Genomes

Researchers at PLOS Biology have examined the coevolution of endogenous parvoviral elements and animal genomes to gain insight into using the viruses as gene therapy vectors.

Saliva Testing Can Reveal Mosaic CNVs Important in Intellectual Disability

An Australian team has compared the yield of chromosomal microarray testing of both blood and saliva samples for syndromic intellectual disability in the European Journal of Human Genetics.

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.