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Funding Update: Jun 17, 2011

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NIH bioinformatics grants awarded May 11 — June 15, 2011

Project Title: A Computational Analysis of Psychiatric Genetics Data: Pathways and Architecture
Principal Investigator: Askland, Kathleen Dawn
Organization: Butler Hospital
Project Start Date: June 20, 2009
Project End Date: May 31, 2014
Funding Institute: NIMH
FY Total Cost: $184,565


Project Title: Reconstructing Dynamic Regulatory Networks
Principal Investigator: Bar-Joseph, Ziv
Organization: Carnegie-Mellon University
Project Start Date: Aug. 15, 2008
Project End Date: May 31, 2012
Funding Institute: NIGMS
FY Total Cost: $280,990


Project Title: Software Integration Between JSim and the Systems Biology Workbench
Principal Investigator: Bassingthwaighte, James
Organization: University of Washington
Project Start Date: June 1, 2009
Project End Date: May 31, 2013
Funding Institute: NIBIB
FY Total Cost: $323,700


Project Title: Clinical and Translational Science Coordinating Center
Principal Investigator: Joskow, Renee
Organization: Vanderbilt University
Project Start Date: June 1, 2011
Project End Date: May 31, 2016
Funding Institute: NCRR
FY Total Cost: $3,988,000


Project Title: Gene Prediction by Markov Models and Complementary Methods
Principal Investigator: Borodovsky, Mark
Organization: Georgia Institute of Technology
Project Start Date: March 15, 1993
Project End Date: May 31, 2013
Funding Institute: NHGRI
FY Total Cost: $577,264


Project Title: Statistical Methods and Software for QTL Mapping
Principal Investigator: Broman, Karl
Organization: University of Wisconsin, Madison
Project Start Date: June 1, 2005
Project End Date: May 31, 2014
Funding Institute: NIGMS
FY Total Cost: $274,940


Project Title: CRCNS: Ontology-Based Multi-scale Integration of the Autism Phenome
Principal Investigator: Das, Amarendra
Organization: Stanford University
Project Start Date: Sept. 4, 2009
Project End Date: April 30, 2012
Funding Institute: NIMH
FY Total Cost: $323,887


Project Title: IBCSG Statistical Center – A Breast Cancer Study Resource
Principal Investigator: Gelber, Richard
Organization: Dana-Farber Cancer Institute
Project Start Date: Sept. 30, 1997
Project End Date: Dec. 31, 2011
Funding Institute: NCI
FY Total Cost: $481,054


Project Title: Software to Identify Post-Translational Modification from Proteomic Datasets
Principal Investigator: Giddings, Morgan Corinne
Organization: Boise State University
Project Start Date: Sept. 24, 2004
Project End Date: Nov. 30, 2011
Funding Institute: NCRR
FY Total Cost: $257,475


Project Title: Developing Proteogenomic Mapping for Human Genome Annotation
Principal Investigator: Giddings, Morgan Corinne
Organization: Boise State University
Project Start Date: Sept. 16, 2005
Project End Date: March 31, 2012
Funding Institute: NHGRI
FY Total Cost: $431,250


Project Title: South Dakota Biomedical Research Infrastructure Network
Principal Investigator: Goodman, Barbara
Organization: University of South Dakota
Project Start Date: Sept. 24, 2001
Project End Date: April 30, 2014
Funding Institute: NCRR
FY Total Cost: $2,907,790


Project Title: The Statistical and Computational Analysis of Flow Cytometry Data
Principal Investigator: Gottardo, Raphael
Organization: Fred Hutchinson Cancer Research Center
Project Start Date: May 1, 2008
Project End Date: April 30, 2012
Funding Institute: NIBIB
FY Total Cost: $359,403


Project Title: Metabolomics Tools for Biomedicine
Principal Investigator: Grant, David Franklin
Organization: University of Connecticut, Storrs
Project Start Date: June 1, 2010
Project End Date: May 31, 2014
Funding Institute: NIGMS
FY Total Cost: $296,858


Project Title: Statistical Methods to Assess the Role of Rare Variants in Complex Traits
Principal Investigator: Ionita, Iuliana
Organization: Columbia University Health Sciences
Project Start Date: Aug. 16, 2010
Project End Date: May 31, 2012
Funding Institute: NHGRI
FY Total Cost: $80,500


Project Title: IDEA Network for Biomedical Research Excellence
Principal Investigator: Kenyon, James
Organization: University of Nevada, Reno
Project Start Date: Sept. 1, 2001
Project End Date: May 31, 2015
Funding Institute: NCRR
FY Total Cost: $2,695,866


Project Title: Accurate Computational Detection of Influenza Reassortments
Principal Investigator: Kingsford, Carleton Lee
Organization: University of Maryland, College Park
Project Start Date: June 1, 2010
Project End Date: May 31, 2012
Funding Institute: NIAID
FY Total Cost: $183,645


Project Title: Statistical Methods for Genomic and Proteomic Data
Principal Investigator: Pan, Wei
Organization: University of Minnesota, Twin Cities
Project Start Date: July 1, 2000
Project End Date: May 31, 2013
Funding Institute: NHLBI
FY Total Cost: $179,369


Project Title: The Gene Wiki Community Intelligence Applied to Gene Annotation
Principal Investigator: Su, Andrew
Organization: Novartis Institute for Functional Genomics
Project Start Date: August1, 2010
Project End Date: May 31, 2014
Funding Institute: NIGMS
FY Total Cost: $266,507


Project Title: Bayesian Methods for Genome-Wide Interacting QTL Mapping
Principal Investigator: Yi, Nengjun
Organization: University of Alabama, Birmingham
Project Start Date: June 1, 2005
Project End Date: May 31, 2014
Funding Institute: NIGMS
FY Total Cost: $302,320


The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.