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Funding Update: Apr 15, 2011 (rev. 1)

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Project Title: Integrated, Interdisciplinary, Inter-University PhD Program in Computational Biology
Principal Investigator: Bahar, Ivet
Organization: University of Pittsburgh at Pittsburgh
Project Start Date: April 1, 2009
Project End Date: March 31, 2014
Funding Institute:NIBIB
FY Total Cost: $351,901


Project Title: High Resolution Structure Modeling with Rosetta
Principal Investigator: Baker, David
Organization: University of Washington
Project Start Date: April 1, 2010
Project End Date: March 31, 2014
Funding Institute: NIGMS
FY Total Cost: $265,524


Project Title: Structure-Based Prediction of the Interactome
Principal Investigator: Berger, Bonnie
Organization: Massachusetts Institute of Technology
Project Start Date: April 1, 2008
Project End Date: March 31, 2012
Funding Institute: NIGMS
FY Total Cost: $263,564


Project Title: Bioscholar: A Biomedical Knowledge Engineering Framework Based on the Published Literature
Principal Investigator: Burns, Gully
Organization: University of Southern California
Project Start Date: April 1, 2008
Project End Date: March 31, 2012
Funding Institute: NIGMS
FY Total Cost: $232,789


Project Title: Multiple Protein Structures in Computational Drug Design
Principal Investigator: Carlson, Heather
Organization: University of Michigan at Ann Arbor
Project Start Date: April 1, 2002
Project End Date: March 31, 2014
Funding Institute: NIGMS
FY Total Cost: $250,366


Project Title: Pharmacogenomics and Antiarrhythmic Therapy: An in Silico Investigation
Principal Investigator: Clancy, Colleen
Organization: University of California Davis
Project Start Date: April 15, 2007
Project End Date: March 31, 2012
Funding Institute: NHLBI
FY Total Cost: $306,750


Project Title: Computational Model of Gene Regulatory Program
Principal Investigator: Davidson, Eric
Organization: California Institute of Technology
Project Start Date: April 1, 2000
Project End Date: March 31, 2012
Funding Institute: NIGMS
FY Total Cost: $350,175


Project Title: Bayesian Statistics and Algorithms for Homology Modeling
Principal Investigator: Dunbrack, Roland L
Organization: Institute for Cancer Research
Project Start Date: May 15, 2008
Project End Date: March 31, 2012
Funding Institute: NIGMS
FY Total Cost: $279,863


Project Title: Computational Genomics of Signal Transduction
Principal Investigator: Jouline, Igor
Organization: University of Tennessee Knoxville
Project Start Date: Sept. 6, 2004
Project End Date: March 31, 2014
Funding Institute: NIGMS
FY Total Cost: $254,566


Project Title: Geometric-Based and Physics-Based Simulations of RNA Folding
Principal Investigator: Koehl, Patrice
Organization: University of California Davis
Project Start Date: April 1, 2007
Project End Date: March 31, 2012
Funding Institute: NIGMS
FY Total Cost: $250,426


Project Title: Statistical Methods for Gene Mapping
Principal Investigator: Lange, Kenneth
Organization: University of California Los Angeles
Project Start Date: Aug. 1, 1995
Project End Date: March 31, 2012
Funding Institute: NIGMS
FY Total Cost: $521,545


Project Title: Training in Ophthalmic Statistical Genetics and Bioinformatics
Principal Investigator: Lee, Hongzhe
Organization: University of Pennsylvania
Project Start Date: April 1, 2011
Project End Date: March 31, 2016
Funding Institute: NEI
FY Total Cost: $114,782


Project Title: Statistical Methods for Correlated and High-Dimensional Biomedical Data
Principal Investigator: Lin, Xihong
Organization: Harvard University (School of Public Health)
Project Start Date: Dec. 15, 1997
Project End Date: March 31, 2016
Funding Institute: NCI
FY Total Cost: $292,927


Project Title: Bayesian Methods in Signal Transduction Network Analysis
Principal Investigator: Liu, Yin
Organization: University of Texas Health Science Center Houston
Project Start Date: March 15, 2011
Project End Date: March 14, 2015
Funding Institute: NLM
FY Total Cost: $235,076


Project Title: Network-Directed Discovery of Disease Genes
Principal Investigator: Marcotte, Edward
Organization: University of Texas Austin
Project Start Date: April 1, 2003
Project End Date: March 31, 2013
Funding Institute: NIGMS
FY Total Cost: $243,778


Project Title: Simulation Models for Diffusion over Multirelational Dynamic Networks
Principal Investigator: Moody, James
Organization: Duke University
Project Start Date: April 1, 2011
Project End Date: March 31, 2013
Funding Institute: NICHD
FY Total Cost: $191,539


Project Title: Collaborative Development of Biomedical Ontologies and Terminologies
Principal Investigator: Musen, Mark
Organization: Stanford University
Project Start Date: March 1, 2009
Project End Date: Feb. 28, 2013
Funding Institute: NIGMS
FY Total Cost: $478,772


Project Title: Autodock Software Development and Maintenance
Principal Investigator: Olson, Arthur
Organization: Scripps Research Institute
Project Start Date: Jan. 1, 2004
Project End Date: March 31, 2012
Funding Institute: NIGMS
FY Total Cost: $473,957


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Project Title: Powerful Inference and Prediction for Genetic Association
Principal Investigator: Pan, Wei
Organization: University of Minnesota Twin Cities
Project Start Date: March 10, 2011
Project End Date: Dec. 31, 2014
Funding Institute: NHLBI
FY Total Cost: $354,066


Project Title: [email protected]: Simulating Folding on the Millisecond To Second Timescale
Principal Investigator: Pande, Vijay
Organization: Stanford University
Project Start Date: July 1, 2002
Project End Date: March 31, 2015
Funding Institute: NIGMS
FY Total Cost: $359,477


Project Title: Refinement Methods for Protein Docking Based on Exploring Multi-Dimensional Energy
Principal Investigator: Paschalidis, Ioannis
Organization: Boston University
Project Start Date: April 1, 2010
Project End Date: March 31, 2015
Funding Institute: NIGMS
FY Total Cost: $286,504


Project Title: Network Analysis of Signal Transduction
Principal Investigator: Perrimon, Norbert
Organization: Harvard University (Medical School)
Project Start Date: April 15, 2010
Project End Date: March 31, 2015
Funding Institute: NIDDK
FY Total Cost: $448,776


Project Title: Integrated Modeling of Protein and Membrane Traffic in the Secretory Pathway
Principal Investigator: Phair, Robert
Organization: Integrative Bioinformatics
Project Start Date: July 1, 2006
Project End Date: March 31, 2014
Funding Institute: NIGMS
FY Total Cost: $181,521


Project Title: Algorithms for Molecular Kinetics
Principal Investigator: Qin, Feng
Organization: State University of New York at Buffalo
Project Start Date: June 1, 2009
Project End Date: March 30, 2013
Funding Institute: NIGMS
FY Total Cost: $443,089


Project Title: IMP: Software for Hybrid Determination of Macromolecular Assembly Structures
Principal Investigator: Sali, Andrej
Organization: University of California San Francisco
Project Start Date: April 1, 2008
Project End Date: March 31, 2012
Funding Institute: NIGMS
FY Total Cost: $247,787


Project Title: Statistical & Computational Tools for Reconstruction of Gene Regulatory Networks
Principal Investigator: Salzman, Peter
Organization: University of Rochester
Project Start Date: Jan. 1, 2009
Project End Date: Aug. 17, 2011
Funding Institute: NLM
FY Total Cost: $86,774


Project Title: Computational Design of Inhibitor Specificity
Principal Investigator: Tidor, Bruce
Organization: Massachusetts Institute of Technology
Project Start Date: April 1, 2009
Project End Date: March 31, 2013
Funding Institute: NIGMS
FY Total Cost: $195,590


Project Title: Glycoprotein Modeling System for Internal Coordinate Mechanics
Principal Investigator: Totrov, Maxim
Organization: Molsoft
Project Start Date: April 1, 2010
Project End Date: March 31, 2012
Funding Institute: NIGMS
FY Total Cost: $199,542


Project Title: Computational Mapping of Proteins for the Binding of Ligands
Principal Investigator: Vajda, Sandor
Organization: Boston University
Project Start Date: Feb. 1, 2003
Project End Date: March 31, 2015
Funding Institute: NIGMS
FY Total Cost: $354,731


Project Title: Statistical Methods for DNA Methylation Data
Principal Investigator: Wang, Shuang
Organization: Columbia University Health Sciences
Project Start Date: April 1, 2010
Project End Date: March 31, 2012
Funding Institute: NCI
FY Total Cost: $72,450


Project Title: Empirical-Bayesian Testing for Family Genome-Wide Association Data
Principal Investigator: Wang, Tao
Organization: Albert Einstein College of Medicine, Yeshiva University
Project Start Date: April 6, 2011
Project End Date: Jan. 31, 2013
Funding Institute: NHGRI
FY Total Cost: $166,000


Project Title: Combined Computational and Experimental Analyses of Gene Regulation By MicroRNAs
Principal Investigator: Wang, Xiaowei
Organization: Washington University
Project Start Date: April 1, 2010
Project End Date: March 31, 2015
Funding Institute: NIGMS
FY Total Cost: $273,600


Project Title: Computer Simulation of Enzymatic Reactions
Principal Investigator: Warshel, Arieh
Organization: University of Southern California
Project Start Date: Jan. 1, 1978
Project End Date: March 31, 2014
Funding Institute: NIGMS
FY Total Cost: $279,862


Project Title: Computational Resources for the Compilation and Distribution of Transcription Factors
Principal Investigator: Wasserman, Wyeth W
Organization: University of British Columbia
Project Start Date: April 15, 2010
Project End Date: March 31, 2013
Funding Institute: NIGMS
FY Total Cost: $302,293


Project Title: Analysis of Genomic Data for Complex Traits
Principal Investigator: Zhang, Heping
Organization: Yale University
Project Start Date: July 1, 2003
Project End Date: March 31, 2012
Funding Institute: NIDA
FY Total Cost: $294,921


Project Title: I-Tasser Based Atomic-Level Protein Structure Prediction
Principal Investigator: Zhang, Yang
Organization: University of Michigan at Ann Arbor
Project Start Date: April 1, 2008
Project End Date: March 31, 2013
Funding Institute: NIGMS
FY Total Cost: $232,645