PARIS--ExonHit Therapeutics, the inventor of a gene profiling technology called Differential Analysis of Transcripts Alternatively Spliced, has introduced a predictive toxicology tool to enhance pharmaceutical and agrochemical research and development. Safe-Hit is a nucleic acid array that incorporates a library of genetic signaturesselected for being affected when cells and tissues are subjected to toxic stresses. A software module in the product reads the microarray, interprets results, and ranks compounds by toxicity.

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Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.