PARIS--ExonHit Therapeutics, the inventor of a gene profiling technology called Differential Analysis of Transcripts Alternatively Spliced, has introduced a predictive toxicology tool to enhance pharmaceutical and agrochemical research and development. Safe-Hit is a nucleic acid array that incorporates a library of genetic signaturesselected for being affected when cells and tissues are subjected to toxic stresses. A software module in the product reads the microarray, interprets results, and ranks compounds by toxicity.