Skip to main content
Premium Trial:

Request an Annual Quote

European Partner's Polymorphism Database Now Available on Web

Premium

UPPSALA, Sweden--Uppsala University's Department of Genetics and Pathology and Interactiva Biotechnologie, headquartered in Ulm, Germany, recently introduced the polymorphism database HGBASE. The database is a catalogue of intragenic sequence variants found in normal individuals that contains all types of gene-based variations, not just biallelic single-nucleotide polymorphisms. Functionally consequential polymorphisms, such as promoter and nonsilent codon changes,and other polymorphisms, such as intron sequence differences, are included. Tools are provided to conduct searches that utilize a text string or a DNA sequence. All submitted data are made available to other public databases. Depositing data within HGBASE requires only the allelic DNA sequence, the allele frequencies, the host gene name, and the intragenic domain. For more information, see http://hgbase.interactiva.de/.

Filed under

The Scan

Study Reveals New Details About Genetics of Major Cause of Female Infertility

Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.

Circulating Tumor DNA Shows Potential as Biomarker in Rare Childhood Cancer

A study in the Journal of Clinical Oncology has found that circulating tumor DNA levels in rhabdomyosarcoma may serve as a biomarker for prognosis.

Study Recommends Cancer Screening for Dogs Beginning Age Seven, Depending on Breed

PetDx researchers report in PLOS One that annual cancer screening for dogs should begin by age seven.

White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds

A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.