UPPSALA, Sweden--Uppsala University's Department of Genetics and Pathology and Interactiva Biotechnologie, headquartered in Ulm, Germany, recently introduced the polymorphism database HGBASE. The database is a catalogue of intragenic sequence variants found in normal individuals that contains all types of gene-based variations, not just biallelic single-nucleotide polymorphisms. Functionally consequential polymorphisms, such as promoter and nonsilent codon changes,and other polymorphisms, such as intron sequence differences, are included. Tools are provided to conduct searches that utilize a text string or a DNA sequence. All submitted data are made available to other public databases. Depositing data within HGBASE requires only the allelic DNA sequence, the allele frequencies, the host gene name, and the intragenic domain. For more information, see http://hgbase.interactiva.de/.
European Partner's Polymorphism Database Now Available on Web
Nov 21, 1998