NEW YORK (GenomeWeb) – A project that brought together computational methods and modeling approaches from dozens of research groups suggests common SNP profiling is likely not the most promising avenue for unearthing markers for predicting treatment response in individuals with rheumatoid arthritis.

Researchers from more than 70 teams put forth modeling methods to evaluate the possibility of using SNP profiles to predict response to so-called anti-TNF treatments, which target the tumor necrosis factor-alpha inflammatory cytokine in individuals with rheumatoid arthritis. 

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.

Nov
05
Sponsored by
Sophia Genetics

With the Next Generation Sequencing (NGS), genomes sequencing has been democratized over the last decades with the detection of genomic alterations, thus replacing Sanger sequencing.