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Downloads & Upgrades: Jan 23, 2009


The National Center of Biotechnology Information has released RefSeq Release 33, which is available here.

This release includes genomic, transcript, and protein data as of Jan. 16, 2008, and includes 10,325,282 records, 6,413,124 proteins, and sequences from 7,773 different organisms. This release is provided as a complete dataset or subdivided into groups.

This release adds targeted transcript records for microbial genomes. The RefSeq targeted loci project includes molecular markers used for phylogenetic analyses. This project is part of an international collaboration with a number of ribosomal RNA databases with an initial scope to comparing curated 16S markers that correspond to type strains and near full length sequences from all contributing databases.

Symyx Technologies has released Notebook 6.1, which supports analytical chemistry and biology workflows.

The company said that Symyx Notebook 6.1 offers time savings along with improved data collection, security, and compliance and is configurable for many scientific disciplines out of the box in regulated and non-regulated environments.

Symyx Draw 3.1 software is embedded in the notebook for chemists to draw and edit chemical structures. The version is integrated with laboratory information management systems and data repositories. By augmenting experimental write-ups with hyperlinks to many related experiments,

Workflow tools in Symyx Notebook 6.1 let users perform document reviews by automatically highlighting invalid or overridden data, out-of-range values, and required fields that lack data entries.

Affymetrix announced via the Affymetrix Developers' Network that the Fusion software development kit has been updated to support the DMET Console 1.0 software.

The latest release of the Fusion SDK, version 1.0.12, includes support for results files generated by DMET Console 1.0 and new functions for parsing CDF files in support of analyzing ADME drug metabolism biomarkers on the DMET Plus Array. In addition, the C++ source code is now compliant with C++ 4.3.

DMET Console 1.0 can be found here.

Affymetrix said that an update to its Power Tools suite of command-line programs is slated for late January. This release will also include a bug fix for the CNCHP file headers so that they can be loaded into the Genotyping Console Software.

Filed under

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.