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Downloads & Upgrades: Jul 2, 2010

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SoftGenetics has released the newest version of its NextGENe software.

According to the company, NextGENe v 2.0 “incorporates a multitude of new features, functionalities and efficiencies requested by biologists, and compatibility with GRCh37.”

Upgrades to the software include a Variant Confidence Scoring Tool that scores variants by four different factors providing a useful method for filtering out low confidence variant calls and a Variant Comparison Tool which compares up to 10 patients or samples.

The company said that in addition to being available in the software, the upgrades are also incorporated in the latest version of the NextGENe Viewer.


The Biotechnology Center of Oslo has released iRefScape 0.90, a Cytoscape plug-in that allows users to search protein interaction data that has been consolidated from multiple databases including BIND, BioGrid, IntAct, MINT, MPPI, and OPHID.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.