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Downloads & Upgrades: Jul 2, 2010

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SoftGenetics has released the newest version of its NextGENe software.

According to the company, NextGENe v 2.0 “incorporates a multitude of new features, functionalities and efficiencies requested by biologists, and compatibility with GRCh37.”

Upgrades to the software include a Variant Confidence Scoring Tool that scores variants by four different factors providing a useful method for filtering out low confidence variant calls and a Variant Comparison Tool which compares up to 10 patients or samples.

The company said that in addition to being available in the software, the upgrades are also incorporated in the latest version of the NextGENe Viewer.


The Biotechnology Center of Oslo has released iRefScape 0.90, a Cytoscape plug-in that allows users to search protein interaction data that has been consolidated from multiple databases including BIND, BioGrid, IntAct, MINT, MPPI, and OPHID.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.