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Downloads & Upgrades: Oct 28, 2011


IO Informatics has launched Knowledge Explorer 3.6, an upgrade of its flagship data-management platform.

The new release offers drag-and-drop ontology management and merging. It also includes an extended application programming interface that allows external developers to write open source or commercial plug-ins for the platform. In addition, it offers performance and search functionality for ontology classes.

IDBS has launched the Omics Workbench, a web-based data-management platform that supports next-generation sequencing and other omics data.

Omics Workbench includes pre-built analytics, visualization, and workflows for all types of omics data including gene expression and copy number variation from sequencing platforms and microarrays.

The platform offers secondary and tertiary analysis of next-gen sequencing data and includes "scientist-oriented" displays to highlight genetic variants between cohort groups, the company said.

Omics Workbench can be deployed on site or hosted in a cloud infrastructure.

The Bioinformatics Research Group at SRI International has released version 15.5 of the BioCyc, EcoCyc, and MetaCyc databases here.

Version 15.5 of BioCyc contains 1,700 pathway/genome databases, including 414 complete bacterial genomes from the Human Microbiome Project.

EcoCyc now includes a functional steady-state metabolic flux model for Escherichia coli produced using flux-balance analysis, while MetaCyc 15.5 contains 1,790 metabolic pathways and 9,600 reactions drawn from 31,000 publications.

The Scan

Pfizer-BioNTech Seek Full Vaccine Approval

According to the New York Times, Pfizer and BioNTech are seeking full US Food and Drug Administration approval for their SARS-CoV-2 vaccine.

Viral Integration Study Critiqued

Science writes that a paper reporting that SARS-CoV-2 can occasionally integrate into the host genome is drawing criticism.

Giraffe Species Debate

The Scientist reports that a new analysis aiming to end the discussion of how many giraffe species there are has only continued it.

Science Papers Examine Factors Shaping SARS-CoV-2 Spread, Give Insight Into Bacterial Evolution

In Science this week: genomic analysis points to role of human behavior in SARS-CoV-2 spread, and more.