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Downloads & Upgrades: Oct 28, 2011

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IO Informatics has launched Knowledge Explorer 3.6, an upgrade of its flagship data-management platform.

The new release offers drag-and-drop ontology management and merging. It also includes an extended application programming interface that allows external developers to write open source or commercial plug-ins for the platform. In addition, it offers performance and search functionality for ontology classes.


IDBS has launched the Omics Workbench, a web-based data-management platform that supports next-generation sequencing and other omics data.

Omics Workbench includes pre-built analytics, visualization, and workflows for all types of omics data including gene expression and copy number variation from sequencing platforms and microarrays.

The platform offers secondary and tertiary analysis of next-gen sequencing data and includes "scientist-oriented" displays to highlight genetic variants between cohort groups, the company said.

Omics Workbench can be deployed on site or hosted in a cloud infrastructure.


The Bioinformatics Research Group at SRI International has released version 15.5 of the BioCyc, EcoCyc, and MetaCyc databases here.

Version 15.5 of BioCyc contains 1,700 pathway/genome databases, including 414 complete bacterial genomes from the Human Microbiome Project.

EcoCyc now includes a functional steady-state metabolic flux model for Escherichia coli produced using flux-balance analysis, while MetaCyc 15.5 contains 1,790 metabolic pathways and 9,600 reactions drawn from 31,000 publications.


The Scan

More Boosters for US

Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes.

From a Pig

A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports.

For Privacy's Sake

Wired reports that more US states are passing genetic privacy laws.

Science Paper on How Poaching Drove Evolution in African Elephants

In Science this week: poaching has led to the rapid evolution of tuskless African elephants.