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Downloads & Upgrades: Jan 16, 2009


Thermo Fisher Scientific last week launched the Comet v3.0 BioApplication, which is the firm's new image processing tool for high content screening through its Cellomics BioApplication product line.

The tool automates the detection and analysis of the single cell gel electrophoresis assay, which is used by toxicologists studying DNA damage. This assay is intended as a companion tool to the Micronucleus BioApplication for scientists to profile compounds in terms of cytotoxicity and genotoxicity endpoints in an automated fashion.

Thermo Fisher said that it will soon be releasing the ZebraTox v3.0 BioApplication, which addresses acute toxicity seen in developing zebrafish embryos.

This new module will allow for multiple measurements to determine shape changes in zebrafish embryos along with the capability to look at fluorescent measurements of targets.

MacVector has released MacVector 10.5. The new version of the desktop sequence analysis application includes an "Align To Reference" tool that scientists can use to align cDNAs to genomic sequences to help identify splice sites and introns.

This version also builds on the new interface first introduced in MacVector 10, with customizable toolbars, a new multi-pane "Preferences" option and popup menu paths on window title bars.

Users will find better support for the Mac OS X file system, including the use of long file names, the company said, along with minor enhancements designed to simplify using MacVector under OS X. The Assembler module has been updated too, with easier editing of reads and contigs, and a new view to enable printing of contigs.

StarLIMS announced that its laboratory information management system StarLIMS V10 R2 is now certified to integrate SAP ERP 6.0 via enterprise services. This level of certification means that StarLIMS can be "integrated with a very wide variety of SAP applications," the company said.

According to the company, this new SAP certification is for web-based integration using StarLIMS' ability to expose and consume web services.

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The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.