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DNA2.0 has launched Gene Designer 2.0, a free software tool for designing novel DNA sequences.

The new version includes an improved graphic interface and drag-and-drop functionality for creating genes, the company said.

The software includes algorithms for in silico cloning, codon optimization, back-translation, and primer design, as well as a customizable database to store, manage, and track genetic elements, genes, and constructs.


Release 104 of the European Nucleotide Archive is available from the European Bioinformatics Institute's ftp site and other mirror sites.

The release contains 190,119,871 sequence entries comprising 287,946,554,761
nucleotides.

Release 104 files total 136 GB compressed and 985 GB uncompressed.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.