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Downloads and Upgrades: Visomics; Graphite-MicroMégas; ΔΔGui server; MOPED 2.0; and GQ-Dx 2.0


Kitware has launched a beta version of Visomics, an open-source application for genomics, proteomics, transcriptomics, and metabolomics.

The tool provides statistical methods, visualizations, and pre-existing chemical pathway diagrams to help researchers track, store, analyze, and evaluate relationships and behaviors in large numbers of analytes and biomarkers.

Graphite-MicroMégas, a tool for DNA 3D modeling, is available here.

The tool lets users generate three-dimensional assemblies of proteins and DNA. Specifically, users can create isosurfaces of molecular objects; highlight residues of interest; import and export in 3D formats; and model DNA and export the results to the Protein Data Bank, among other capabilities.

The Office of Cyber Infrastructure and Computational Biology at the National Institute of Allergy and Infectious Diseases has released the ΔΔGui server, an interface for the Rosetta macromolecular modeling suite.

The tool is expected to help users answer questions such as the effect of mutations on the stability and binding energy of proteins.

MOPED 2.0 is available here.

The release has several improvements including data storage for private datasets; enhanced pathway coverage; mouse data; and links to PubMed articles among other features

GenomeQuest has released GQ-Dx 2.0, an updated version of its genomic decision support system for molecular laboratories.

This version includes tools that researchers in molecular laboratories can use to produce diagnostic reports from next generation sequence data (see related article, this issue).

The Scan

Highly Similar

Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News.

Gain of Oversight

According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research.

Lasker for mRNA Vaccine Work

The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners

PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC

In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.