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Downloads and Upgrades: VectorFriends1.1, UCSC Genome Browser; Ensembl Genomes 20, and more

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Singapore-based BioFriends(Pte Ltd) has launched VectorFriends 1.1, the latest version of its software for sequence analysis and in silico molecular biology.

The software provides cloning capabilities such as isothermal assembly, TOPO PCR cloning, and restriction cloning; as well as tools for sequence data analysis including sequence alignment, Sanger sequence assembly, open reading frame analysis and GC plot analysis. It also provides a hierarchical folder structure for managing data and tools to backup and retrieve information.


This week, the genome browser group at the University of California, Santa Cruz released new browsers for the sheep, Ovis aries, and the lesser hedgehog tenrec, Echinops telfairi assemblies.

Bulk downloads of the sequence and annotation data are available via the genome browser ftp server or the downloads page.


Release 20 of Ensembl Genomes is available here.

The release includes new genomes and/or updated assemblies in Ensembl fungi, Ensembl plants, Ensembl bacteria, Ensembl metazoan and Ensembl protists.


ACD/Labs has launched the ACD/ChemAnalytical workbook, a new software application on its Spectrus platform that offers tools for managing research experiments, workflows, and data.


Accelrys has released new version of its data cartridge, chemical registration, and biological registration programs.

Accelrys Direct Data cartridge 9.0 offers improved chemistry representation and search capabilities; Accelrys Chemical Registration 3.2 provides an interface to the Accelrys Electronic Lab Notebook enabling direct registration from experiments; and Accelrys Biological Registration 3.1 provides new capabilities for defining chemically modified biological entities such as PEGylated peptides and antibody drug conjugates through support for chemical structure attributes, chemistry attribute rules, and chemistry searching.


The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.