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Downloads and Upgrades: VectorFriends1.1, UCSC Genome Browser; Ensembl Genomes 20, and more


Singapore-based BioFriends(Pte Ltd) has launched VectorFriends 1.1, the latest version of its software for sequence analysis and in silico molecular biology.

The software provides cloning capabilities such as isothermal assembly, TOPO PCR cloning, and restriction cloning; as well as tools for sequence data analysis including sequence alignment, Sanger sequence assembly, open reading frame analysis and GC plot analysis. It also provides a hierarchical folder structure for managing data and tools to backup and retrieve information.

This week, the genome browser group at the University of California, Santa Cruz released new browsers for the sheep, Ovis aries, and the lesser hedgehog tenrec, Echinops telfairi assemblies.

Bulk downloads of the sequence and annotation data are available via the genome browser ftp server or the downloads page.

Release 20 of Ensembl Genomes is available here.

The release includes new genomes and/or updated assemblies in Ensembl fungi, Ensembl plants, Ensembl bacteria, Ensembl metazoan and Ensembl protists.

ACD/Labs has launched the ACD/ChemAnalytical workbook, a new software application on its Spectrus platform that offers tools for managing research experiments, workflows, and data.

Accelrys has released new version of its data cartridge, chemical registration, and biological registration programs.

Accelrys Direct Data cartridge 9.0 offers improved chemistry representation and search capabilities; Accelrys Chemical Registration 3.2 provides an interface to the Accelrys Electronic Lab Notebook enabling direct registration from experiments; and Accelrys Biological Registration 3.1 provides new capabilities for defining chemically modified biological entities such as PEGylated peptides and antibody drug conjugates through support for chemical structure attributes, chemistry attribute rules, and chemistry searching.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.