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Downloads and Upgrades: UCSC Genome Browser and RefSeq 66

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The bioinformatics group at the University of California, Santa Cruz has released assemblies for pika (Ochotona princeps) and shrew (Sorex araneus).

Bulk downloads of the sequence and annotation data are available via the Genome Browser ftp server or from the downloads page.


RefSeq 66 is now available from the National Center for Biotechnology Information via ftp.

This release has nearly 59 million records describing 43,671,159 proteins, 7,568,770 RNAs, and sequences from 41,263 different NCBI Taxons.

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The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.