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Downloads and Upgrades: Tera-BLAST, Oncomine Gene Browser, Ion Reporter Oncomine Workflow, and more

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Active Motif's TimeLogic has released an updated version of Tera-BLAST, its field programmable gate array-based implementation of the Basic Local Alignment Search Tool.

According to the company, the new version of Tera-BLAST delivers over 1,200x speed-up compared to running software-only versions of BLAST.


Genevestigator is offering a free resource that contains curated public expression data from more than 1,400 different types of cancer and 245 human healthy tissues


BioCyc 17.0 is available here.

This release includes updates to the BioCyc website, including new additions to the EcoCyc and MetaCyc databases, downloadable data files, and a downloadable Pathway Tools software/database bundle.


This week, Life Technologies launched the Oncomine Gene Browser and the Ion Reporter Oncomine Workflow, two new bioinformatics solutions for cancer research that are based on the Oncomine platform which was developed by Compendia Bioscience, an Ann Arbor, Mich.-based company which Life Tech acquired in 2012 (BI 10/12/2012).

Oncomine Gene Browser enables cancer researchers in academia, biotech, and small pharmaceutical companies to characterize their genes of interest across multiple parameters, including gene expression, DNA copy number and mutation data, from thousands of cancer patients' exomes and transcriptomes. It is ideal for researchers working with small numbers of genes and enables the survey of individual genes across thousands of de-identified clinical cases and dozens of different cancer types and subtypes.

The Ion Reporter Oncomine Workflow solution combines the Oncomine platform with Life Tech's Ion Reporter software and provides access to curated next generation sequencing data from 4,000 matched tumor and normal pairs. It is designed to help researchers interpret variants from data obtained on the Ion Torrent sequencing platforms.


The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.