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Downloads and Upgrades: Spectronaut, Omicia's Phevor, and more


Biognosys, a swiss proteomics company, said this week that the new version of Spectronaut, its software for analyzing hyper reaction monitoring data, now enables customers automatically generate spectral libraries using search results from Thermo Scientific's Proteome Discoverer platform. Spectronaut is free for academic researchers who can obtain software licenses at Biognosys’ online shop.

Omicia said this week that it is integrating its Phenotype Driven Variant Ontological Re-ranking (Phevor) tool, an algorithm for identifying disease-relevant variants in genomic data, into Opal, its software-as-a-service genome interpretation platform. The addition of Phevor will support direct integration of patient symptoms and condition information into Opal, which in turn will help users further prioritize genetic variants.

Beckman Coulter Genomics, a firm that provides genomics solutions to research and healthcare institutions, has integrated Genologics' Clarity Laboratory Information Management System into the HiSeq-based workflows it offers for next-generation sequencing to provide clients with tools for managing data and methods.

OpenEye's AFITT 2.4 is now available for download. This release of the crystallographic refinement program includes features such as the ability to fit covalently bound ligands and the availability of fast protein side chain fitting to the command line.

The Scan

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.

Neurological Outcomes Linked to Innate Immune Features After Cardiac Arrest

Researchers reporting in Med dig into immune features found a few hours after cardiac arrest that correspond with neurological outcomes.

Mouse Study Finds Circadian Rhythm-Related Gene Expression Changes Linked to Sleep Apnea

A paper in PLOS Biology reveals tissue-specific circadian rhythm and gene expression patterns in an intermittent hypoxia-based mouse model of obstructive sleep apnea.

Polygenic Risk Score to Predict Preeclampsia, Gestational Hypertension in Pregnant Women

Researchers in Nature Medicine provide new mechanistic insights into the development of hypertensive disorders of pregnancy, which may help develop therapeutics.