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Downloads and Upgrades: Simcyp Simulator 13, rtgSingleton and rtgPopulation beta, and more


Certara has released version 13 of the Simcyp Simulator, its software for quantitative prediction of drug-drug-interactions and pharmacokinetic-pharmacodynamic outcomes in virtual populations.

The release includes a physiologically-based pharmacokinetic model for monoclonal antibodies and therapeutic proteins, and a non-linear plasma protein and red blood cell binding facility among other features.

Real Time Genomics released its rtgSingleton product for analyzing individual genomic samples, and a beta version of its rtgPopulation product for case-control and cohort applications.

The singleton product is designed to analyze panels, exomes, or genomes on a case-by-case basis while the population product is designed for analyzing large numbers of samples.

The human genome annotation release 105 is now available from the National Center for Biotechnology Information.

Annotated genomic, transcript, and protein records are available through the integrated Entrez system and may be downloaded via ftp or the Aspera protocol.

OpenEye Scientific Software has released QUACPAC 1.6

This release incorporates several improvements as well as bug fixes.

Simulations Plus has released GastroPlus 8.5, the latest version of its pharmacokinetic and pharmacodynamic simulation software.

The release includes a new mechanistic precipitation model and a new method for transporter-based in vitro-in vivo extrapolation among other updates.

BioJava Legacy 1.8.4 is available here as well as from the BioJava maven repository.

Features in this release include minor improvements to the sequencing module as well as build fixes.