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Downloads and Upgrades: RefSeq 65, I2E 4.2, and more


RefSeq 65 is now available from the National Center for Biotechnology Information via FTP.

This release incorporates genomic, transcript, and protein data available as of May 12, 2014. It includes 51,770,174 records, 38,633,935 proteins, 7,051,549 RNAs, and sequences from 36,335 different organisms.

Linguamatics has released I2E 4.2, the latest version of its text mining platform. The release includes tools for integrated charting and graphing of data and new capabilities for integrating semantically enriched data into enterprise search engines.

Dassault Systèmes has launched a new tool called Biovia that combines capabilities from its own portfolio with assets it's acquired when it merged with Accelrys earlier this year. The solution provides tools for biological, chemical and material modeling, simulation and production domains.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.