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Downloads and Upgrades: RealTime StatMiner 5.0, Genome Workbench 2.7.15, and more


Integromics has released a new version of RealTime StatMiner, its software for analyzing data from qPCR experiments.

According to the company, version 5.0 has an improved data loader that better handles large data files from a variety of instrument platforms, and it has a new method for normalizing data across multiple plates. Also included is a new interactive Principal Component Analysis tool as well as new features for reporting analysis results, such as the automatic generation of gene lists showing altered expression between conditions and multiple comparison visualizations.

The National Center for Biotechnology Information has released Genome Workbench 2.7.15, an application for viewing and analyzing sequence data.

The updated version of the software includes new features such as a multiple alignment view, an active objects inspector, and binary packages for Linux OpenSUSE 13.1. Additional information on features, fixes, and improvements are available in the release notes.

The National Institutes of Health has made genetic data linked to medical information from the Genetic Epidemiology Research on Aging (GERA) project available in the database of genotypes and phenotypes.

The GERA project contains data from a cohort of more 78,000 individuals with an average age of 63. It is part of the Research Program on Genes, Environment, and Health, which includes more than 430,000 adult members of the Kaiser Permanente Northern California system.

Ensembl release 75 is available here.

The release includes a new VEP interface, a new track for human data, an updated Zebrafish gene set, new RNA-seq data for mouse, and more.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.