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Downloads and Upgrades: OpenLAB ELN 4.2, RefSeq 62, SRA-BLAST, and Linguamatics Health


Agilent Technologies has released a new version of its electronic laboratory notebook software.

OpenLAB ELN 4.2 helps users capture, reuse, manage, and share their scientific results. It includes drag and drop capabilities and it lets users copy and paste content. It also features a virtual printer that captures scientific results in PDF format from any application.

RefSeq 62 is now available from the National Center for Biotechnology Information via FTP.

The release has nearly 50 million records including more than 36,036,343 proteins and 5,178,509 transcripts from 31,646 different organisms. More details about release 62 are in the release statistics and the release notes.

NCBI has also added to new features to its SRA-BLAST tool, which is used to explore data stored in NCBI’s Sequence Read Archive.

This includes expanding SRA-BLAST search capabilities to support data from additional sequencing technologies beyond the Roche 454 system. Experiments that can be searched through BLAST now include data from all current next-sequencing technologies that produce read lengths long enough for general BLAST searching. Also SRA-BLAST now offers two different ways of finding data sets to search.

Linguamatics has launched Linguamatics Health, a new clinical natural language processing suite that enables hospitals and research organizations access the information contained in unstructured electronic health record data and patient narratives.

According to the company, the suite, which includes Linguamatics I2E, the company’s existing product, provides tools to extract meaningful information from the data located in complex patient documentation such as pathology and radiology reports, physician notes, and discharge reports.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.