Skip to main content
Premium Trial:

Request an Annual Quote

Downloads and Upgrades: OpenEye Toolkits v2012.Oct; Ensembl Genomes; and Bowtie 2 2.0.1


OpenEye has released OpenEye Toolkits v2012.Oct.

This release includes the C++, Python, and .NET versions of several toolkits.

The full release notes are available here.

The toolkits can be downloaded here.

Release 16 of Ensembl Genomes is available here.

The release includes a migration to version 69 of the Ensembl software; the addition of several new species in Ensembl plants and Ensembl metazoan; improvements to the wheat assembly; and the ability to highlight annotations in gene trees among other updates.

Bowtie 2 2.0.1 is available here.

The release fixes several bugs as well as an issue that would cause Bowtie 2 to use excessive amounts of memory for closely matching and highly repetitive reads under some circumstances, among other improvements.

Filed under

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.