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Downloads and Upgrades: Omics Explorer 3.0, ADMET Predictor 7.0, and more

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Qlucore has released Omics Explorer 3.0.

This latest version of the company's software includes a new Gene Ontology browser, a Gene Set Enrichment Analysis workbench, and new file import functionality for aligned RNA-seq data.


Simulations Plus has released ADMET Predictor 7.0, the latest version of its program predicting molecular properties from structure.

The release includes a new pKa model developed in collaboration with Bayer HealthCare, retrained predictive models, and it implements news algorithms to select the best artificial neural network model among other updates


Reactome 47 is available here.

Topics with new or revised events include cellular response to stress, cell cycle, immune system, metabolism of proteins, and signal transduction.


The National Center for Biotechnology Information has released Genome Workbench 2.7.12.

This version of the software includes new features like a faster tree renderer, redesigned data import, and an improved GFF format reader. The release notes include more information on features, fixes and improvements.

The NCBI is also offering NCBI Remap, a genome remapping tool that lets users map annotation data from one genomic assembly to another for a selected set of organisms.


The Genome Bioinformatics group at the University of California, Santa Cruz, has added two new assembly hubs to its collection of publicly available hubs.

These new hubs feature over 60 bacterial assemblies, including more than 55 different E. coli strains. The assembly annotations include genes, pathogenic genes, conservation, GC percent, repetitive elements, and much more.


The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.