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Downloads and Upgrades: Lasergene 10, StarDrop 5.2, BASE 3.1, EMBL-Bank 111, Labguru

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DNAStar has released Lasergene 10, the latest version of its sequence analysis and assembly software.

The release includes SeqNinja, which lets uses manipulate and modify genomic datasets as well as edit sequence data and annotations. It also provides support for assembling and analyzing data from Ion Torrent and Pacific Biosciences data; tools to incorporate data from dbSNP, Cosmic, and GERP databases into sequence assembly and analysis projects; the ability to create custom SNP tables; and tools to detect splice site sequence variations.

Lasergene 10 also integrates GenVision into the Lasergene Core Suite, so that users have the ability to create graphics of integrated data sets.


Optibrium has launched StarDrop 5.2, which includes the first fruits of a collaboration between Optibrium and Cresset.

The release includes a new plug-in module that provides users with access to Cresset’s FieldAlign technology, which offers three-dimensional insight into the biological activity of compounds. The release also includes a tool for performing automatic R-group analysis.


Version 3.1 of the BioArray Software Environment (BASE) is available here.

The release includes an improved user interface; the ability to clone reporter information to a local copy per experiment; and a migration script for moving a BASE installation from MySQL to PostgreSQL


Release 111 of the European Nucleotide Archive/EMBL-Bank is available from the European Bioinformatics Institute’s ftp servers and other mirror sites.

Full release notes are available here.


BioData has integrated about 50 protocols from Sigma Life Science into its Labguru web service, which will be available free of charge to its customers.

The update provides bench scientists with a set of peer-reviewed protocols to use or adapt for their experiments. They include steps and procedures as well as associated kits, reagents, and materials; optional timers and alarms for each step; and the ability to conduct multiple simultaneous experiments.


The Scan

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.

Analysis of Endogenous Parvoviral Elements Found Within Animal Genomes

Researchers at PLOS Biology have examined the coevolution of endogenous parvoviral elements and animal genomes to gain insight into using the viruses as gene therapy vectors.

Saliva Testing Can Reveal Mosaic CNVs Important in Intellectual Disability

An Australian team has compared the yield of chromosomal microarray testing of both blood and saliva samples for syndromic intellectual disability in the European Journal of Human Genetics.

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.