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Downloads and Upgrades: Labguru2, Geneious R6.1, ENCODE Analysis Data Hub, and more

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This week, BioData released Labguru 2, the latest version of its life science research and lab management software.

This version of the tool has simpler menus and navigation tools, a live feed of ongoing research in the lab, a whiteboard for sharing important messages, a more comprehensive storage module to help users locate and track items in the lab, and bulk tagging and organization tools, among other updates.


Biomatters has released Geneious R6.1, the latest version of its DNA, RNA, and protein sequence alignment, assembly, and analysis software.

The release includes applications for automatically annotating plasmids and other sequences, an improved reference assembly algorithm, and a new cloning primer design tool, among other updates.


An updated version of the Encyclopedia of DNA Elements' Analysis Data Hub is available here.

The ENCODE Analysis Data Hub hosts uniformly processed files produced by the ENCODE analysis working group. This release includes new metadata that has been added to the data tracks, and offers a supplementary metadata file for download. It also includes updates to the ENCODE portal downloads page that make the resource more accessible.


A beta version of the Cytoscape Network Inference, or Cyni, Toolbox is available for download from the Cytoscape app store.

Cyni is a collection of tools for biological network inference. It provides several commonly used network inference techniques, data imputation and discretization techniques, and a documented application programming interface.


A web server for analyzing hidden stops in frame-shifted translations, dubbed SHIFT, is available here.


The Scan

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.

EHR Quality Improvement Study Detects Demographic-Related Deficiencies in Cancer Family History Data

In a retrospective analysis in JAMA Network Open, researchers find that sex, ethnicity, language, and other features coincide with the quality of cancer family history information in a patient's record.

Inflammatory Bowel Disease Linked to Gut Microbiome Community Structure Gradient in Meta-Analysis

Bringing together data from prior studies, researchers in Genome Biology track down microbial taxa and a population structure gradient with ties to ulcerative colitis or Crohn's disease.

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.