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Downloads and Upgrades: IMPROVER COPD Models and KnoSys 3.0


The organizers of the sbvIMPROVER project have released a set of comprehensive biological models for chronic obstructive pulmonary disease for review by the global scientific community. These models were generated for the first phase of the group's Network Verification challenge.

These models, the organizers said, could be used to assess the mechanistic actions of new drug compounds and also to develop "robust hypotheses of gene expression changes and pathway activation/quiescence."

Knome has released a third version of KnoSYS, its genomic interpretation solution. This version of the software works independently of Knome’s hardware and includes new features such as an updated interface, new reference data sources, improved database server functionality, and other updates.

In addition to the new software release, Knome now offers pay-as-you-go pricing for its solution.

The Scan

Gone, But Now Reconstructed SARS-CoV-2 Genomes

In a preprint, a researcher describes his recovery of viral sequences that had been removed from a common database.

Rare Heart Inflammation Warning

The Food and Drug Administration is adding a warning about links between a rare inflammatory heart condition and two SARS-CoV-2 vaccines, Reuters reports.

Sandwich Sampling

The New York Times sent tuna sandwiches for PCR analysis.

Nature Papers Describe Gut Viruses, New Format for Storing Quantitative Genomic Data, More

In Nature this week: catalog of DNA viruses of the human gut microbiome, new dense depth data dump format to store quantitative genomic data, and more.