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Downloads and Upgrades: Human CCDS 15 and NEBioCalculator


The National Center for Biotechnology has released a Consensus Coding Sequence update for Homo sapiens annotation release 105. The update is available on the CCDS website and via FTP.

The release adds 349 new CCDS IDs to the human CCDS dataset and is based on comparative analysis of NCBI Homo sapiens annotation release 105 and Ensembl release 74. The human CCDS dataset now includes 29,045 proteins that correspond to 18,683 genes.

New England Biolabs has released NEBioCalculator, a collection of web-based calculators and converters that are useful in planning bench experiments in molecular biology laboratories.

The NEBioCalculator supports molarity calculation, OD260 conversion, ligation calculation, and mass/moles conversion for both dsDNA and ssRNA, and more. It provides calculations based on user-specified units. Scientists can input their measurements in milligram, microgram, nanogram or picogram amounts, leading to accurate calculations that require no further conversion.

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The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.