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Downloads and Upgrades: Genedata Biologics 2.5, BROC plug-in, Myrna 1.2.0, and More


Genedata has released Genedata Biologics 2.5, the latest version of its enterprise solution for biologics research and development.

The release includes extended sequence annotation capabilities including interfaces for registration of advanced custom annotation workflows for antibody engineering; out-of-the-box sequence analysis workflows for high-throughput antibody reformatting and other molecular biology activities; comprehensive antibody hierarchy reporting; and high-throughput protein expression sample processing among other features.

CLC Bio and BioFormatix have released a Bootstrapped Receiver Operating Characteristic, or BROC, plug-in for CLC Main Workbench and CLC Genomics Workbench.
The plug-in will help users analyze differentially expressed probes in microarray experiments.

The ENCODE Data Coordination Center at the University of California, Santa Cruz, has released new data tracks for the hg19 genome browser. These include 53 additional experiments, with 22 new cell lines from different RNA populations; and transcription levels assayed by RNA sequencing on nine cell lines among other updates

UCSC’s genome informatics group has released a new genome browser for the Tasmanian devil assembly

Bulk downloads of the sequence and annotation data are available via ftp or on the downloads page.

Myrna 1.2.0 is available here.

The release includes added support for Hadoop 0.20.205, updated versions of Bowtie and R, and bug fixes among other changes.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.